2-Benzenesulfonyl-2-[(3aS,5S,6aR)-5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-hexahydro-cyclopenta[b]furan-4-yl]-1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanol

Base Information

Chemical Name:2-Benzenesulfonyl-2-[(3aS,5S,6aR)-5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-hexahydro-cyclopenta[b]furan-4-yl]-1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanol
CAS No.:105394-07-8
Molecular Formula:C₂₇H₄₄O₈SSi
Molecular Weight:556.793
Hs Code.:

2-Benzenesulfonyl-2-[(3aS,5S,6aR)-5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-hexahydro-cyclopenta[b]furan-4-yl]-1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanol

Synonyms:

Suppliers and Price of 2-Benzenesulfonyl-2-[(3aS,5S,6aR)-5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-hexahydro-cyclopenta[b]furan-4-yl]-1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Benzenesulfonyl-2-[(3aS,5S,6aR)-5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-hexahydro-cyclopenta[b]furan-4-yl]-1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Benzenesulfonyl-2-[(3aS,5S,6aR)-5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-hexahydro-cyclopenta[b]furan-4-yl]-1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanol

There total 8 articles about 2-Benzenesulfonyl-2-[(3aS,5S,6aR)-5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-hexahydro-cyclopenta[b]furan-4-yl]-1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 86021-78-5,105455-57-0,105455-58-1,118919-53-2,118919-54-3
(3aS,5S,6aR)-4-Phenylsulfanylmethyl-hexahydro-cyclopenta[b]furan-2,5-diol

: 105394-07-8
2-Benzenesulfonyl-2-[(3aS,5S,6aR)-5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-hexahydro-cyclopenta[b]furan-4-yl]-1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanol

Guidance literature:: Multi-step reaction with 4 steps

1: 95 percent / BF₃*Et₂O / -20 °C

2: 88 percent / imidazol / dimethylformamide / 40 °C

3: mClPBA / CH₂Cl₂ / -78 °C

With 1H-imidazole; 3-chloro-benzenecarboperoxoic acid; boron trifluoride diethyl etherate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(01)80897-2

Reference yield:

: 86021-69-4,91739-11-6,118919-52-1
(3aS,5S,6aR)-5-Hydroxy-4-phenylsulfanylmethyl-hexahydro-cyclopenta[b]furan-2-one

: 105394-07-8
2-Benzenesulfonyl-2-[(3aS,5S,6aR)-5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-hexahydro-cyclopenta[b]furan-4-yl]-1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanol

Guidance literature:: Multi-step reaction with 5 steps

1: 75 percent / DIBAL / CH₂Cl₂ / -78 °C

2: 95 percent / BF₃*Et₂O / -20 °C

3: 88 percent / imidazol / dimethylformamide / 40 °C

4: mClPBA / CH₂Cl₂ / -78 °C

With 1H-imidazole; diisobutylaluminium hydride; 3-chloro-benzenecarboperoxoic acid; boron trifluoride diethyl etherate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(01)80897-2

Reference yield:

: 105394-12-5,118919-51-0
Toluene-4-sulfonic acid (3aS,5S,6aR)-5-hydroxy-2-oxo-hexahydro-cyclopenta[b]furan-4-ylmethyl ester

: 105394-07-8
2-Benzenesulfonyl-2-[(3aS,5S,6aR)-5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-hexahydro-cyclopenta[b]furan-4-yl]-1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanol

Guidance literature:: Multi-step reaction with 6 steps

1: 98 percent / t-BuOK / dimethylsulfoxide / 0.5 h / Ambient temperature

2: 75 percent / DIBAL / CH₂Cl₂ / -78 °C

3: 95 percent / BF₃*Et₂O / -20 °C

4: 88 percent / imidazol / dimethylformamide / 40 °C

5: mClPBA / CH₂Cl₂ / -78 °C

With 1H-imidazole; potassium tert-butylate; diisobutylaluminium hydride; 3-chloro-benzenecarboperoxoic acid; boron trifluoride diethyl etherate; In dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(01)80897-2