5beta-Cholane-3alpha,7beta,24-triol

Base Information

Chemical Name:5beta-Cholane-3alpha,7beta,24-triol
CAS No.:130593-75-8
Molecular Formula:C₂₄H₄₂O₃
Molecular Weight:378.596
Hs Code.:
UNII:49AM7E73PT
Nikkaji Number:J496.505A
Metabolomics Workbench ID:36550
ChEMBL ID:CHEMBL1253814

Synonyms:130593-75-8;5beta-Cholane-3alpha,7beta,24-triol;(3alpha,5beta,7beta)-Cholane-3,7,24-triol;49AM7E73PT;UNII-49AM7E73PT;CHEMBL1253814;Ursodeoxycholic acid impurity I [EP];(3R,5S,7S,8R,9S,10S,13R,14S,17R)-17-[(2R)-5-hydroxypentan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol;Cholane-3,7,24-triol, (3alpha,5beta,7beta)-;LMST04010313;UDC-OH;BDBM50423620;5.BETA.-CHOLANE-3.ALPHA.,7.BETA.,24-TRIOL;URSODEOXYCHOLIC ACID IMPURITY I [EP IMPURITY];(3.ALPHA.,5.BETA.,7.BETA.)-CHOLANE-3,7,24-TRIOL;CHOLANE-3,7,24-TRIOL, (3.ALPHA.,5.BETA.,7.BETA.)-

Suppliers and Price of 5beta-Cholane-3alpha,7beta,24-triol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3α,5β,7β)-Cholane-3,7,24-triol
25mg
$ 100.00

Medical Isotopes, Inc.
5-beta-Cholane-3-α-7-beta-24-triol
25 mg
$ 190.00

Biosynth Carbosynth
(3α,5β,7β)-Cholane-3,7,24-triol
100 mg
$ 300.00

Biosynth Carbosynth
(3α,5β,7β)-Cholane-3,7,24-triol
50 mg
$ 200.00

Biosynth Carbosynth
(3α,5β,7β)-Cholane-3,7,24-triol
25 mg
$ 160.00

Biosynth Carbosynth
(3α,5β,7β)-Cholane-3,7,24-triol
10 mg
$ 100.00

Biosynth Carbosynth
(3α,5β,7β)-Cholane-3,7,24-triol
5 mg
$ 60.00

Total 11 raw suppliers

Chemical Property of 5beta-Cholane-3alpha,7beta,24-triol

Chemical Property:

Melting Point:>80°C (dec.)
Boiling Point:509.5±25.0 °C(Predicted)
Density:1.079±0.06 g/cm3(Predicted)
XLogP3:5.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:378.31339520
Heavy Atom Count:27
Complexity:536

Purity/Quality:

99.99%HPLC ^*data from raw suppliers

(3α,5β,7β)-Cholane-3,7,24-triol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(CCCO)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C
Isomeric SMILES:C[C@H](CCCO)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C
Uses (3α,5β,7β)-Cholane-3,7,24-triol (Ursodeoxycholic Acid EP Impurity I) is used in the preparation of Ursodeoxycholic Acid (U850000) scaffold. Ursodeoxycholic Acid scaffold is used to generate novel and selective steroidal ligands for GP-BAR1, a promising pharmacology target for the treatment of steatohepatitis, type 2 diabetes, and obesity.

Technology Process of 5beta-Cholane-3alpha,7beta,24-triol

There total 5 articles about 5beta-Cholane-3alpha,7beta,24-triol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1537866-58-2
3α,7β-di(tert-butyldimethylsilyloxy)-5β-cholan-24-ol

: 23848-46-6,130593-75-8
UDC-OH

Guidance literature:: With hydrogenchloride; In methanol; water; at 20 ℃; for 2h;
DOI:10.1021/jm401873d

Reference yield: 94.0%

: 128-13-2
ursodeoxycholic acid

: 23848-46-6,130593-75-8
UDC-OH

Guidance literature:: With samarium diiodide; water; triethylamine; In tetrahydrofuran; at 20 ℃; for 4h; Inert atmosphere;
DOI:10.1021/ol203361k