6--2-cyclohexenone

Base Information

• Chemical Name: 6--2-cyclohexenone
• CAS No.: 85448-22-2
• Molecular Formula: C₉H₈F₆O₂
• Molecular Weight: 262.152
• Mol file: 85448-22-2.mol

Synonyms:

Chemical Property of 6--2-cyclohexenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6--2-cyclohexenone

There total 1 articles about 6--2-cyclohexenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(trimethylsiloxy)cyclohexa-1,3-diene (54781-19-0) + Hexafluoroacetone (684-16-2) → 6--2-cyclohexenone (85448-22-2)

Guidance literature:

With hydrogenchloride; titanium tetrachloride; Yield given. Multistep reaction; 1.) THF, -45 to -40 deg C, 2.) dioxane, 95 deg C, 24 h;

DOI:10.1016/S0022-1139(00)81485-2

Reference yield: 90.0%

lithium dimethylcuprate (15681-48-8) + 6--2-cyclohexenone (85448-22-2) → 2--5-methylcyclohexanone

Guidance literature:

In diethyl ether; -50 deg C, 20 min then room temp., 40 min;

DOI:10.1016/S0022-1139(00)81485-2

Reference yield:

6--2-cyclohexenone (85448-22-2) → 2-hexafluoroisopropylidene-5-methylcyclohexanone

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / diethyl ether / -50 deg C, 20 min then room temp., 40 min

2: 76 percent / pyridine, methyl chlorosulfite / tetrahydrofuran / 36 h

With pyridine; chlorosulfite de methyle; In tetrahydrofuran; diethyl ether;

DOI:10.1016/S0022-1139(00)81485-2

upstream raw materials:

2-(trimethylsiloxy)cyclohexa-1,3-diene

Hexafluoroacetone