Technology Process of C10H10O3*C8H11N
There total 6 articles about C10H10O3*C8H11N which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: thionyl chloride / 12 h / Reflux
2.1: potassium carbonate; sodium iodide / N,N-dimethyl-formamide / 12 h / 20 °C
3.1: neat (no solvent) / 2 h / 160 °C
4.1: zirconium(IV) chloride / dichloromethane / 10 h / 20 °C
5.1: sodium hydroxide / methanol / 2 h / Reflux
5.2: 0 °C / pH 1
6.1: methanol
With
thionyl chloride; zirconium(IV) chloride; potassium carbonate; sodium iodide; sodium hydroxide;
In
methanol; dichloromethane; N,N-dimethyl-formamide;
3.1: |Claisen Rearrangement;
DOI:10.1021/jm5002502
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium carbonate; sodium iodide / N,N-dimethyl-formamide / 12 h / 20 °C
2.1: neat (no solvent) / 2 h / 160 °C
3.1: zirconium(IV) chloride / dichloromethane / 10 h / 20 °C
4.1: sodium hydroxide / methanol / 2 h / Reflux
4.2: 0 °C / pH 1
5.1: methanol
With
zirconium(IV) chloride; potassium carbonate; sodium iodide; sodium hydroxide;
In
methanol; dichloromethane; N,N-dimethyl-formamide;
2.1: |Claisen Rearrangement;
DOI:10.1021/jm5002502
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: neat (no solvent) / 2 h / 160 °C
2.1: zirconium(IV) chloride / dichloromethane / 10 h / 20 °C
3.1: sodium hydroxide / methanol / 2 h / Reflux
3.2: 0 °C / pH 1
4.1: methanol
With
zirconium(IV) chloride; sodium hydroxide;
In
methanol; dichloromethane;
1.1: |Claisen Rearrangement;
DOI:10.1021/jm5002502
