HydroxylaMine, O-[(2-Methylphenyl)Methyl]-, hydrochloride

Base Information

• Chemical Name: HydroxylaMine, O-[(2-Methylphenyl)Methyl]-, hydrochloride
• CAS No.: 115777-56-5
• Molecular Formula: C₈H₁₁NO*ClH
• Molecular Weight: 173.642
• Hs Code.: 2928009090
• Mol file: 115777-56-5.mol

Synonyms:

Chemical Property of HydroxylaMine, O-[(2-Methylphenyl)Methyl]-, hydrochloride

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

O-(2-Methylbenzyl)hydroxylamine hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of HydroxylaMine, O-[(2-Methylphenyl)Methyl]-, hydrochloride

There total 4 articles about HydroxylaMine, O-[(2-Methylphenyl)Methyl]-, hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.4%

C10H13NO2 → O-(o-methyl)-benzyl-hydroxyamine hydrochloride (115777-56-5)

Guidance literature:

With hydrogenchloride; In ethanol; water; at 65 ℃;

Reference yield:

2-((2-methylbenzyl)oxy)isoindoline-1,3-dione (681160-67-8) → O-(o-methyl)-benzyl-hydroxyamine hydrochloride (115777-56-5)

Guidance literature:

With hydrogenchloride; acetic acid; In water;

DOI:10.24820/ark.5550190.p010.472

Reference yield:

1-chloromethyl-2-methylbenzene (552-45-4) → O-(o-methyl)-benzyl-hydroxyamine hydrochloride (115777-56-5)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydrogencarbonate; tetra(n-butyl)ammonium hydrogensulfate / water; dichloromethane / 40 °C

2: acetic acid; hydrogenchloride / water

With hydrogenchloride; tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate; acetic acid; In dichloromethane; water;

DOI:10.24820/ark.5550190.p010.472

upstream raw materials:

2-((2-methylbenzyl)oxy)isoindoline-1,3-dione

1-chloromethyl-2-methylbenzene

2-methylbenzyl bromide

Refernces

• 1、 Johnson, Alyssa L.,Duncan, Nathan,Mosher, Michael D.. "O-benzyl-N-(9-acridinyl)hydroxylamines". . p. 139 - 148. Retrieved 2018.