1-<2-(4-bromo-4'-fluorobenzhydryloxy)ethyl>-4-(3-<2-(4-bromo-4'-fluorobenzhydryloxy)ethyl>-2-oxo-benzimidazol-1-yl)-1,2,3,6-tetrahydropyridine

Base Information

• Chemical Name: 1-<2-(4-bromo-4'-fluorobenzhydryloxy)ethyl>-4-(3-<2-(4-bromo-4'-fluorobenzhydryloxy)ethyl>-2-oxo-benzimidazol-1-yl)-1,2,3,6-tetrahydropyridine
• CAS No.: 96122-92-8
• Molecular Formula: C₄₂H₃₇Br₂F₂N₃O₃
• Molecular Weight: 829.579
• Mol file: 96122-92-8.mol

Synonyms:

Chemical Property of 1-<2-(4-bromo-4'-fluorobenzhydryloxy)ethyl>-4-(3-<2-(4-bromo-4'-fluorobenzhydryloxy)ethyl>-2-oxo-benzimidazol-1-yl)-1,2,3,6-tetrahydropyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-<2-(4-bromo-4'-fluorobenzhydryloxy)ethyl>-4-(3-<2-(4-bromo-4'-fluorobenzhydryloxy)ethyl>-2-oxo-benzimidazol-1-yl)-1,2,3,6-tetrahydropyridine

There total 2 articles about 1-<2-(4-bromo-4'-fluorobenzhydryloxy)ethyl>-4-(3-<2-(4-bromo-4'-fluorobenzhydryloxy)ethyl>-2-oxo-benzimidazol-1-yl)-1,2,3,6-tetrahydropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

4-bromo-4'-fluorobenzhydryl 2-bromoethyl ether (96122-88-2) + 1,3-dihydro-1-(1,2,3,6-tetrahydro-4-pyridinyl)-2H-benzimidazol-2-one (2147-83-3) → 1-<2-(4-bromo-4'-fluorobenzhydryloxy)ethyl>-4-(3-<2-(4-bromo-4'-fluorobenzhydryloxy)ethyl>-2-oxo-benzimidazol-1-yl)-1,2,3,6-tetrahydropyridine (96122-92-8)

Guidance literature:

With potassium carbonate; In various solvent(s);

DOI:10.1135/cccc19842649

Reference yield:

4-bromo-4'-fluorodiphenylmethanol (3851-47-6) → 1-<2-(4-bromo-4'-fluorobenzhydryloxy)ethyl>-4-(3-<2-(4-bromo-4'-fluorobenzhydryloxy)ethyl>-2-oxo-benzimidazol-1-yl)-1,2,3,6-tetrahydropyridine (96122-92-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / H₂SO₄ / benzene

2: 23 percent / K₂CO₃ / various solvent(s)

With sulfuric acid; potassium carbonate; In benzene;

DOI:10.1135/cccc19842649

upstream raw materials:

4-bromo-4'-fluorobenzhydryl 2-bromoethyl ether

1,3-dihydro-1-(1,2,3,6-tetrahydro-4-pyridinyl)-2H-benzimidazol-2-one

4-bromo-4'-fluorodiphenylmethanol