Technology Process of 2-<3-Methyl-5-(2,6,6-trimethyl-1-cyclohexenyl)-2,4-pentadienylidene>hexanedinitrile
There total 2 articles about 2-<3-Methyl-5-(2,6,6-trimethyl-1-cyclohexenyl)-2,4-pentadienylidene>hexanedinitrile which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: LDA / tetrahydrofuran; hexane / 1.) -80 deg C, 30 min; -80 to -45 deg C, 1.5 h, 2.) HMPA, -45 deg C, 10 min
2: tetrahydrofuran; hexane; hexamethylphosphoric acid triamide / 12 h / Ambient temperature
With
lithium diisopropyl amide;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane;
DOI:10.1002/recl.19941130107
- Guidance literature:
-
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane;
for 12h;
Yield given;
Ambient temperature;
DOI:10.1002/recl.19941130107
- Guidance literature:
-
Multi-step reaction with 2 steps
1: Dibal / petroleum ether; hexane / 1.) -70 deg C, 1 h, 2.) -20 deg C
2: aq. acetic acid, SiO2 / petroleum ether; diethyl ether / 72 h
With
silica gel; diisobutylaluminium hydride; acetic acid;
In
diethyl ether; hexane; Petroleum ether;
DOI:10.1002/recl.19941130107
