benzyl 2-(benzyloxycarbonylamino)-2,6-dideoxy-6-(eicosanoylamino)-3-O--5-O-(tetrahydropyran-2-yl)-β-D-glucofuranoside

Base Information

• Chemical Name: benzyl 2-(benzyloxycarbonylamino)-2,6-dideoxy-6-(eicosanoylamino)-3-O--5-O-(tetrahydropyran-2-yl)-β-D-glucofuranoside
• CAS No.: 82816-54-4
• Molecular Formula: C₅₀H₇₈N₂O₁₀
• Molecular Weight: 867.177

Synonyms:

Chemical Property of benzyl 2-(benzyloxycarbonylamino)-2,6-dideoxy-6-(eicosanoylamino)-3-O--5-O-(tetrahydropyran-2-yl)-β-D-glucofuranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl 2-(benzyloxycarbonylamino)-2,6-dideoxy-6-(eicosanoylamino)-3-O--5-O-(tetrahydropyran-2-yl)-β-D-glucofuranoside

There total 5 articles about benzyl 2-(benzyloxycarbonylamino)-2,6-dideoxy-6-(eicosanoylamino)-3-O--5-O-(tetrahydropyran-2-yl)-β-D-glucofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl 2-(benzyloxycarbonylamino)-2-deoxy-3-O--β-D-glucofuranoside (81148-68-7) → benzyl 2-(benzyloxycarbonylamino)-2,6-dideoxy-6-(eicosanoylamino)-3-O--5-O-(tetrahydropyran-2-yl)-β-D-glucofuranoside (82816-54-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 89 percent / pyridine / 5 h / -10 °C

2: 96 percent / 1.) p-toluenesulfonic acid monohydrate; 2.) Amberlite IR-45 (OH^-) ion-exchange resin / dioxane / 3 h / Ambient temperature

3: 87 percent / sodium azide / dimethylformamide / 15 h / 80 °C / Heating

4: Raney Ni (W-1) / ethanol / 1.5 h / Ambient temperature

5: dioxane / 5 h / Ambient temperature

With pyridine; sodium azide; Amberlite IR-45 (OH^-) ion-exchange resin; toluene-4-sulfonic acid; Raney Ni (W-1); In 1,4-dioxane; ethanol; N,N-dimethyl-formamide;

DOI:10.1016/S0008-6215(00)80687-4

Reference yield:

benzyl 2-(benzyloxycarbonylamino)-2-deoxy-6-O-mesyl-3-O--β-D-glucofuranoside (81148-76-7) → benzyl 2-(benzyloxycarbonylamino)-2,6-dideoxy-6-(eicosanoylamino)-3-O--5-O-(tetrahydropyran-2-yl)-β-D-glucofuranoside (82816-54-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 96 percent / 1.) p-toluenesulfonic acid monohydrate; 2.) Amberlite IR-45 (OH^-) ion-exchange resin / dioxane / 3 h / Ambient temperature

2: 87 percent / sodium azide / dimethylformamide / 15 h / 80 °C / Heating

3: Raney Ni (W-1) / ethanol / 1.5 h / Ambient temperature

4: dioxane / 5 h / Ambient temperature

With sodium azide; Amberlite IR-45 (OH^-) ion-exchange resin; toluene-4-sulfonic acid; Raney Ni (W-1); In 1,4-dioxane; ethanol; N,N-dimethyl-formamide;

DOI:10.1016/S0008-6215(00)80687-4

Reference yield:

benzyl 2-(benzyloxycarbonylamino)-2-deoxy-6-O-mesyl-3-O--5-O-(tetrahydropyran-2-yl)-β-D-glucofuranoside (81161-19-5) → benzyl 2-(benzyloxycarbonylamino)-2,6-dideoxy-6-(eicosanoylamino)-3-O--5-O-(tetrahydropyran-2-yl)-β-D-glucofuranoside (82816-54-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 87 percent / sodium azide / dimethylformamide / 15 h / 80 °C / Heating

2: Raney Ni (W-1) / ethanol / 1.5 h / Ambient temperature

3: dioxane / 5 h / Ambient temperature

With sodium azide; Raney Ni (W-1); In 1,4-dioxane; ethanol; N,N-dimethyl-formamide;

DOI:10.1016/S0008-6215(00)80687-4

upstream raw materials:

benzyl 2-(benzyloxycarbonylamino)-2-deoxy-3-O--β-D-glucofuranoside

benzyl 2-(benzyloxycarbonylamino)-2-deoxy-6-O-mesyl-3-O--β-D-glucofuranoside

benzyl 6-azido-2-(benzyloxycarbonylamino)-2,6-dideoxy-3-O--5-O-(tetrahydropyran-2-yl)-β-D-glucofuranoside

benzyl 2-(benzyloxycarbonylamino)-2-deoxy-6-O-mesyl-3-O--5-O-(tetrahydropyran-2-yl)-β-D-glucofuranoside

Downstream raw materials:

(R)-2-{(2R,3R,4R,5R)-5-Benzyloxy-2-[(R)-2-icosanoylamino-1-(tetrahydro-pyran-2-yloxy)-ethyl]-4-octanoylamino-tetrahydro-furan-3-yloxy}-propionic acid

benzyl 2,6-dideoxy-6-(eicosanoylamino)-3-O--2-(octanoylamino)-5-O-(tetrahydropyran-2-yl)-β-D-glucofuranoside

(R)-2-{(2R,3R,4R,5R)-5-Benzyloxy-4-icosanoylamino-2-[(R)-2-icosanoylamino-1-(tetrahydro-pyran-2-yloxy)-ethyl]-tetrahydro-furan-3-yloxy}-propionic acid

benzyl 2,6-dideoxy-2,6-di(eicosanoylamino)-3-O--5-O-(tetrahydropyran-2-yl)-β-D-glucofuranoside

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 82816-54-4 benzyl 2-(benzyloxycarbonylamino)-2,6-dideoxy-6-(eicosanoylamino)-3-O--5-O-(tetrahydropyran-2-yl)-β-D-glucofuranoside

Send

Send

Metric Ton KG G Pound L ML

Send

Send