[2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-ylmethyl]-phosphinic acid ethyl ester

Base Information

• Chemical Name: [2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-ylmethyl]-phosphinic acid ethyl ester
• CAS No.: 179017-27-7
• Molecular Formula: C₂₉H₃₉N₂O₆PSi
• Molecular Weight: 570.698

Synonyms:

Chemical Property of [2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-ylmethyl]-phosphinic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-ylmethyl]-phosphinic acid ethyl ester

There total 8 articles about [2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-ylmethyl]-phosphinic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(R)-[(2S,3S,5R)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-ylmethyl]-(1,1-diethoxy-ethyl)-phosphinic acid ethyl ester (179017-24-4) → [2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-ylmethyl]-phosphinic acid ethyl ester (179017-27-7,179017-28-8,195873-28-0)

Guidance literature:

With chloro-trimethyl-silane; ethanol; In dichloromethane; at 20 ℃; for 36h;

DOI:10.1055/s-2001-12329

Reference yield: 87.0%

[2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-ylmethyl]-(1,1-diethoxy-ethyl)-phosphinic acid ethyl ester (195873-29-1) → [2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-ylmethyl]-phosphinic acid ethyl ester (179017-27-7,179017-28-8,195873-28-0)

Guidance literature:

With chloro-trimethyl-silane; ethanol; In chloroform; at 20 ℃;

DOI:10.1055/s-2001-12328

Reference yield:

(S)-[(2S,3S,5R)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-ylmethyl]-(1,1-diethoxy-ethyl)-phosphinic acid ethyl ester (179017-20-0) → [2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-ylmethyl]-phosphinic acid ethyl ester (179017-27-7,179017-28-8,195873-28-0)

Guidance literature:

With chloro-trimethyl-silane; ethanol; In dichloromethane; at 20 ℃;

DOI:10.1055/s-2001-12329

upstream raw materials:

[2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-ylmethyl]-(1,1-diethoxy-ethyl)-phosphinic acid ethyl ester

1-[5-(tert-butyldiphenylsilyl)-2,3-dideoxy-3-C-(formyl)-β-D-erythro-pentofuranosyl]thymine

1-{(3'R,4'S)-5'-O-[(tert-butyl)diphenylsilyl]-2',3'-dideoxy-3'-C-(hydroxymethyl)-β-pentofuranosyl}thymine

5'-O-(tert-butydiphenylsilyl)-3'-deoxy-3'-C-(iodomethyl)thymidine

Downstream raw materials:

[2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-ylmethyl]-phosphinic acid

C₄₀H₅₄N₅O₁₁PSi

C₄₀H₅₄N₅O₁₁PSi

C₄₅H₅₄N₅O₁₃P

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 179017-27-7 [2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-ylmethyl]-phosphinic acid ethyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send