(R)-3-phenylbutanol

Base Information

• Chemical Name: (R)-3-phenylbutanol
• CAS No.: 86495-15-0
• Molecular Formula: C₁₀H₁₄O
• Molecular Weight: 150.221
• Mol file: 86495-15-0.mol

Synonyms:

Chemical Property of (R)-3-phenylbutanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-3-phenylbutanol

There total 47 articles about (R)-3-phenylbutanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(R)-3-phenylbutyric acid (772-14-5) → (R)-3-phenylbutanol (2031-46-1,2722-36-3,86495-15-0,1126-07-4)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1021/jo00177a047

Reference yield: 98.0%

(E)-3-phenylbut-2-en-1-ol (54976-38-4) → (R)-3-phenylbutanol (2031-46-1,2722-36-3,86495-15-0,1126-07-4)

Guidance literature:

With C₃₂H₁₂BF₂₄^(1-)*C₃₇H₄₁IrN₂PS⁽¹⁺⁾; hydrogen; In dichloromethane; at 20 ℃; for 17h; under 37503.8 Torr; enantioselective reaction;

DOI:10.1021/acscatal.6b02456

Reference yield: 91.0%

methyl (R)-3-phenylbutanoate (1472-07-7) → (R)-3-phenylbutanol (2031-46-1,2722-36-3,86495-15-0,1126-07-4)

Guidance literature:

With diisobutylaluminium hydride; In dichloromethane; at -78 - 20 ℃;

DOI:10.1021/ja952835t

upstream raw materials:

3-phenyl-1-butanol

(R)-3-phenylbutyric acid

(R)-2-(1Ξ,2E)-but-2-enylideneamino-3,3-dimethyl-butyric acid tert-butyl ester

3-phenylbut-1-ene

Downstream raw materials:

(+)-(R)-3-cyclohexylbutan-1-ol

(-)(R)-4-bromo-2-phenyl-butane

(-)-(R)-1-Chlor-2-phenyl-butan

3-phenylbutanal