(4Z,4Z')-4,4'-(2,2'-(4,4'-methylenebis(4,1-phenylene)bis(azanediyl))bis(1-hydroxy ethan-2-yl-1-ylidene))bis(3-methyl-1-phenyl-1H-pyrazol-5(4H)-one)

Base Information

• Chemical Name: (4Z,4Z')-4,4'-(2,2'-(4,4'-methylenebis(4,1-phenylene)bis(azanediyl))bis(1-hydroxy ethan-2-yl-1-ylidene))bis(3-methyl-1-phenyl-1H-pyrazol-5(4H)-one)
• CAS No.: 1104635-90-6
• Molecular Formula: C₃₇H₃₄N₆O₄
• Molecular Weight: 626.715
• Mol file: 1104635-90-6.mol

Synonyms:

Chemical Property of (4Z,4Z')-4,4'-(2,2'-(4,4'-methylenebis(4,1-phenylene)bis(azanediyl))bis(1-hydroxy ethan-2-yl-1-ylidene))bis(3-methyl-1-phenyl-1H-pyrazol-5(4H)-one)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4Z,4Z')-4,4'-(2,2'-(4,4'-methylenebis(4,1-phenylene)bis(azanediyl))bis(1-hydroxy ethan-2-yl-1-ylidene))bis(3-methyl-1-phenyl-1H-pyrazol-5(4H)-one)

There total 1 articles about (4Z,4Z')-4,4'-(2,2'-(4,4'-methylenebis(4,1-phenylene)bis(azanediyl))bis(1-hydroxy ethan-2-yl-1-ylidene))bis(3-methyl-1-phenyl-1H-pyrazol-5(4H)-one) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

(Z)-4-(2-chloro-1-hydroxyethylidene)-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one (1104639-33-9) + 4,4'-diamino diphenyl methane (101-77-9) → (4Z,4Z')-4,4'-(2,2'-(4,4'-methylenebis(4,1-phenylene)bis(azanediyl))bis(1-hydroxy ethan-2-yl-1-ylidene))bis(3-methyl-1-phenyl-1H-pyrazol-5(4H)-one) (1104635-90-6)

Guidance literature:

With potassium carbonate; In spirit; for 5 - 7h; Reflux;

DOI:10.1016/j.saa.2008.06.024

Reference yield: 72.0%

nickel(II) nitrate hydrate + (4Z,4Z')-4,4'-(2,2'-(4,4'-methylenebis(4,1-phenylene)bis(azanediyl))bis(1-hydroxy ethan-2-yl-1-ylidene))bis(3-methyl-1-phenyl-1H-pyrazol-5(4H)-one) (1104635-90-6) → [Ni((4Z,4Z')-4,4'-(2,2'-(4,4'-methylenebis(4,1-phenylene)bis(azanediyl))bis(1-hydroxy ethan-2-yl-1-ylidene))bis(3-methyl-1-phenyl-1H-pyrazol-5(4H)-one)(-2H))(H2O)2](n)*2H2O

Guidance literature:

With sodium acetate; In methanol; N,N-dimethyl-formamide; byproducts: HNO3, H2O; ligand dissolved in DMF: soln. of metal salt in MeOH added slowly with stirring over 30 min in 1:1 molar ratio; pH adjusted to 5-6 (soln. of sodium acetate in MeOH); mixt. heated with stirring at reflux temp. for 4-5h; filtered off; washed (hot water, hot MeOH, Et2O); dried in vac. desiccator (over CaCl2); elem anal.;

DOI:10.1016/j.saa.2008.06.024

Reference yield: 70.0%

copper(II) nitrate hydrate + (4Z,4Z')-4,4'-(2,2'-(4,4'-methylenebis(4,1-phenylene)bis(azanediyl))bis(1-hydroxy ethan-2-yl-1-ylidene))bis(3-methyl-1-phenyl-1H-pyrazol-5(4H)-one) (1104635-90-6) → [Cu((4Z,4Z')-4,4'-(2,2'-(4,4'-methylenebis(4,1-phenylene)bis(azanediyl))bis(1-hydroxy ethan-2-yl-1-ylidene))bis(3-methyl-1-phenyl-1H-pyrazol-5(4H)-one)(-2H))(H2O)2](n)*H2O

Guidance literature:

With sodium acetate; In methanol; N,N-dimethyl-formamide; byproducts: HNO3, H2O; ligand dissolved in DMF: soln. of metal salt in MeOH added slowly with stirring over 30 min in 1:1 molar ratio; pH adjusted to 5-6 (soln. of sodium acetate in MeOH); mixt. heated with stirring at reflux temp. for 4-5h; filtered off; washed (hot water, hot MeOH, Et2O); dried in vac. desiccator (over CaCl2); elem anal.;

DOI:10.1016/j.saa.2008.06.024

upstream raw materials:

(Z)-4-(2-chloro-1-hydroxyethylidene)-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one

4,4'-diamino diphenyl methane