2-[(tert-butoxycarbonyl)amino]ethyl bromide-2,2-d2

Base Information

• Chemical Name: 2-[(tert-butoxycarbonyl)amino]ethyl bromide-2,2-d2
• CAS No.: 1141819-53-5
• Molecular Formula: C₇H₁₄BrNO₂
• Molecular Weight: 226.082
• Mol file: 1141819-53-5.mol

Synonyms:

Chemical Property of 2-[(tert-butoxycarbonyl)amino]ethyl bromide-2,2-d2

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[(tert-butoxycarbonyl)amino]ethyl bromide-2,2-d2

There total 1 articles about 2-[(tert-butoxycarbonyl)amino]ethyl bromide-2,2-d2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-[(tert-butoxycarbonyl)amino]ethanol-2,2-d2 (1141819-49-9) → 2-[(tert-butoxycarbonyl)amino]ethyl bromide-2,2-d2 (1141819-53-5)

Guidance literature:

With carbon tetrabromide; triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 2h;

DOI:10.1002/chem.201002759

Reference yield:

2-[(tert-butoxycarbonyl)amino]ethyl bromide-2,2-d2 (1141819-53-5) → C13(13)CH19(2)H2N3O6S

Guidance literature:

Multi-step reaction with 3 steps

1: 18-crown-6 ether / acetonitrile / 9 h / 80 °C

2: platinum(IV) oxide; hydrogen / methanol / 22 h / 20 °C / 3420.23 Torr

3: triethylamine / dichloromethane / 8 h / 20 °C

With platinum(IV) oxide; 18-crown-6 ether; hydrogen; triethylamine; In methanol; dichloromethane; acetonitrile;

DOI:10.1002/chem.201002759

upstream raw materials:

2-[(tert-butoxycarbonyl)amino]ethanol-2,2-d2