2-[4-(Methylsulfinyl)butyl]-1,3-dioxolane

Base Information

• Chemical Name: 2-[4-(Methylsulfinyl)butyl]-1,3-dioxolane
• CAS No.: 1391054-23-1
• Molecular Formula: C₈H₁₆O₃S
• Molecular Weight: 192.279
• Mol file: 1391054-23-1.mol

Synonyms:

Chemical Property of 2-[4-(Methylsulfinyl)butyl]-1,3-dioxolane

Chemical Property:

• Solubility.: Chloroform, Methanol

Purity/Quality:

2-[4-(Methylsulfinyl)butyl]-1,3-dioxolane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Intermediate in the synthesis of Glucoraphanin.

Technology Process of 2-[4-(Methylsulfinyl)butyl]-1,3-dioxolane

There total 5 articles about 2-[4-(Methylsulfinyl)butyl]-1,3-dioxolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2-(4-(methylthio)butyl)-1,3-dioxolane (1453081-14-5) → 2-(4-(methylsulfinyl)butyl)-1,3-dioxolane (1391054-23-1)

Guidance literature:

With sodium periodate; In methanol; water; at 0 ℃; Reagent/catalyst; Solvent; Temperature;

DOI:10.1016/j.tet.2013.07.097

Reference yield:

2-(4-(methylthio)butyl)-1,3-dioxolane (1453081-14-5) → C8H16O4S + 2-(4-(methylsulfinyl)butyl)-1,3-dioxolane (1391054-23-1)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 2h; Reagent/catalyst; Solvent;

DOI:10.1016/j.tet.2013.07.097

Reference yield:

5-methylsulfanyl-pentanal → 2-(4-(methylsulfinyl)butyl)-1,3-dioxolane (1391054-23-1)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / toluene / 3 h / Reflux; Dean-Stark

2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 20 °C

With toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; toluene;

DOI:10.1016/j.tet.2013.07.097

upstream raw materials:

5-chloropentan-1-ol

5-(methylthio)pentan-1-ol

2-(4-(methylthio)butyl)-1,3-dioxolane

Refernces