C₂₀H₃₁NO₄

Base Information

• Chemical Name: C₂₀H₃₁NO₄
• CAS No.: 1606138-31-1
• Molecular Formula: C₂₀H₃₁NO₄
• Molecular Weight: 349.47
• Mol file: 1606138-31-1.mol

Synonyms:

Chemical Property of C₂₀H₃₁NO₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₃₁NO₄

There total 6 articles about C₂₀H₃₁NO₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C20H31NO4 (1606138-29-7) → C20H31NO4 (1606138-31-1)

Guidance literature:

With (R)-3,3'-bis(2,4,6-triisopropylphenyl)binol phosphoric acid; In ethyl acetate; at 40 ℃; for 1.5h; enantioselective reaction; Inert atmosphere;

DOI:10.1021/ja5017206

Reference yield:

tert-butyl carbazate (4248-19-5) → C20H31NO4 (1606138-31-1)

Guidance literature:

Multi-step reaction with 4 steps

1: formic acid / tetrahydrofuran; water / 20 °C / Inert atmosphere

2: neat (no solvent) / 20 °C / Inert atmosphere

3: lithium triethylborohydride; NiI₂(xantphos) / tetrahydrofuran / 20 °C / Inert atmosphere

4: (R)-3,3'-bis(2,4,6-triisopropylphenyl)binol phosphoric acid / ethyl acetate / 1.5 h / 40 °C / Inert atmosphere

With (R)-3,3'-bis(2,4,6-triisopropylphenyl)binol phosphoric acid; formic acid; NiI₂(xantphos); lithium triethylborohydride; In tetrahydrofuran; water; ethyl acetate;

DOI:10.1021/ja5017206

Reference yield:

4-(4-methoxyphenyl)butyraldehyde (56047-51-9) → C20H31NO4 (1606138-31-1)

Guidance literature:

Multi-step reaction with 4 steps

1: formic acid / tetrahydrofuran; water / 20 °C / Inert atmosphere

2: neat (no solvent) / 20 °C / Inert atmosphere

3: lithium triethylborohydride; NiI₂(xantphos) / tetrahydrofuran / 20 °C / Inert atmosphere

4: (R)-3,3'-bis(2,4,6-triisopropylphenyl)binol phosphoric acid / ethyl acetate / 1.5 h / 40 °C / Inert atmosphere

With (R)-3,3'-bis(2,4,6-triisopropylphenyl)binol phosphoric acid; formic acid; NiI₂(xantphos); lithium triethylborohydride; In tetrahydrofuran; water; ethyl acetate;

DOI:10.1021/ja5017206

upstream raw materials:

tert-butyl carbazate

4-(4-methoxyphenyl)butyraldehyde

C₂₂H₂₉NO₅S

C₂₀H₃₁NO₄

Downstream raw materials:

tert-butyl (4R,5R)-5-(hydroxymethyl)-1-(4-methoxyphenyl)heptan-4-ylcarbamate