N-[9-((1R,2S,3S,4R)-2,3-Dihydroxy-4-hydroxymethyl-cyclopentyl)-9H-purin-6-yl]-benzamide

Base Information

Chemical Name:N-[9-((1R,2S,3S,4R)-2,3-Dihydroxy-4-hydroxymethyl-cyclopentyl)-9H-purin-6-yl]-benzamide
CAS No.:133268-28-7
Molecular Formula:C₁₈H₁₉N₅O₄
Molecular Weight:369.38
Hs Code.:

Synonyms:

Suppliers and Price of N-[9-((1R,2S,3S,4R)-2,3-Dihydroxy-4-hydroxymethyl-cyclopentyl)-9H-purin-6-yl]-benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[9-((1R,2S,3S,4R)-2,3-Dihydroxy-4-hydroxymethyl-cyclopentyl)-9H-purin-6-yl]-benzamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[9-((1R,2S,3S,4R)-2,3-Dihydroxy-4-hydroxymethyl-cyclopentyl)-9H-purin-6-yl]-benzamide

There total 12 articles about N-[9-((1R,2S,3S,4R)-2,3-Dihydroxy-4-hydroxymethyl-cyclopentyl)-9H-purin-6-yl]-benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 16346-63-7
(1R,4R)-(+)-norbornenone

: 133268-28-7
N-[9-((1R,2S,3S,4R)-2,3-Dihydroxy-4-hydroxymethyl-cyclopentyl)-9H-purin-6-yl]-benzamide

Guidance literature:: Multi-step reaction with 12 steps

1: 65 percent / H₂O₂, H₂SO₄ / diethyl ether

2: KOH / dioxane / 1 h / Heating

4: Et₃N / acetone

5: NaN₃

6: toluene / 1 h / Heating

7: H₂O

8: 46 percent / NaNO₂ / CH₂Cl₂ / 24 h

9: 82 percent / MCPBA / toluene / 2 h / Heating

10: 46 percent / NaH / dimethylformamide / 48 h / 140 °C

11: NH₃ / methanol

12: H₂ / 5percent Pd/C / ethanol

With potassium hydroxide; sodium azide; sulfuric acid; ammonia; water; hydrogen; dihydrogen peroxide; sodium hydride; triethylamine; 3-chloro-benzenecarboperoxoic acid; sodium nitrite; palladium on activated charcoal; In 1,4-dioxane; methanol; diethyl ether; ethanol; dichloromethane; N,N-dimethyl-formamide; acetone; toluene;
DOI:10.1016/S0040-4039(00)74840-4

Reference yield:

: 133268-26-5
cis-4-Oxa-bicyclo[3.3.0]-7-octen-3-on

: 133268-28-7
N-[9-((1R,2S,3S,4R)-2,3-Dihydroxy-4-hydroxymethyl-cyclopentyl)-9H-purin-6-yl]-benzamide

Guidance literature:: Multi-step reaction with 11 steps

1: KOH / dioxane / 1 h / Heating

3: Et₃N / acetone

4: NaN₃

5: toluene / 1 h / Heating

6: H₂O

7: 46 percent / NaNO₂ / CH₂Cl₂ / 24 h

8: 82 percent / MCPBA / toluene / 2 h / Heating

9: 46 percent / NaH / dimethylformamide / 48 h / 140 °C

10: NH₃ / methanol

11: H₂ / 5percent Pd/C / ethanol

With potassium hydroxide; sodium azide; ammonia; water; hydrogen; sodium hydride; triethylamine; 3-chloro-benzenecarboperoxoic acid; sodium nitrite; palladium on activated charcoal; In 1,4-dioxane; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide; acetone; toluene;
DOI:10.1016/S0040-4039(00)74840-4

Reference yield:

: ((1R,2S)-2-Hydroxy-cyclopent-3-enyl)-acetic acid

: 133268-28-7
N-[9-((1R,2S,3S,4R)-2,3-Dihydroxy-4-hydroxymethyl-cyclopentyl)-9H-purin-6-yl]-benzamide

Guidance literature:: Multi-step reaction with 10 steps

2: Et₃N / acetone

3: NaN₃

4: toluene / 1 h / Heating

5: H₂O

6: 46 percent / NaNO₂ / CH₂Cl₂ / 24 h

7: 82 percent / MCPBA / toluene / 2 h / Heating

8: 46 percent / NaH / dimethylformamide / 48 h / 140 °C

9: NH₃ / methanol

10: H₂ / 5percent Pd/C / ethanol

With sodium azide; ammonia; water; hydrogen; sodium hydride; triethylamine; 3-chloro-benzenecarboperoxoic acid; sodium nitrite; palladium on activated charcoal; In methanol; ethanol; dichloromethane; N,N-dimethyl-formamide; acetone; toluene;
DOI:10.1016/S0040-4039(00)74840-4