sodium 16-oxo-17β-hydroxy-1,3,5(10)-estratrien-3-yl sulfate

Base Information

• Chemical Name: sodium 16-oxo-17β-hydroxy-1,3,5(10)-estratrien-3-yl sulfate
• CAS No.: 81072-43-7
• Molecular Formula: C₁₈H₂₁O₆S*Na
• Molecular Weight: 388.417
• Mol file: 81072-43-7.mol

Synonyms:

Chemical Property of sodium 16-oxo-17β-hydroxy-1,3,5(10)-estratrien-3-yl sulfate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of sodium 16-oxo-17β-hydroxy-1,3,5(10)-estratrien-3-yl sulfate

There total 2 articles about sodium 16-oxo-17β-hydroxy-1,3,5(10)-estratrien-3-yl sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

sodium 17-oxo-16α-hydroxy-1,3,5(10)-estratrien-3-yl sulfate (81072-42-6) → sodium 16-oxo-17β-hydroxy-1,3,5(10)-estratrien-3-yl sulfate (81072-43-7)

Guidance literature:

With sodium hydroxide; In methanol; water; for 12h; Ambient temperature;

DOI:10.1016/0039-128X(81)90054-4

Reference yield:

16alpha-Bromoestrone (71765-95-2) → sodium 16-oxo-17β-hydroxy-1,3,5(10)-estratrien-3-yl sulfate (81072-43-7)

Guidance literature:

With chlorosulfonic acid; sodium hydroxide; Yield given. Multistep reaction; 1.) pyridine, 30 deg C, 2.5 h, 2.) r.t., 12 h;

DOI:10.1016/0039-128X(81)90054-4

upstream raw materials:

16alpha-Bromoestrone

sodium 17-oxo-16α-hydroxy-1,3,5(10)-estratrien-3-yl sulfate

Refernces