GlucNAc acid

Base Information

• Chemical Name: GlucNAc acid
• CAS No.: 1159408-54-4
• Molecular Formula: C₁₉H₂₉NO₁₁
• Molecular Weight: 447.439
• Mol file: 1159408-54-4.mol

Synonyms:

Chemical Property of GlucNAc acid

Chemical Property:

Purity/Quality:

98.0%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of GlucNAc acid

There total 32 articles about GlucNAc acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-benzyloxycarbonylbutyl-2-deoxy-2-N-acetyl-3,4,6-tri-O-acetyl-β-D-galactopyranoside → 5-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pentanoic acid (1159408-54-4)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; ethyl acetate;

Reference yield: 83.0%

C14H25NO8 + acetic anhydride (108-24-7) → 5-(((2S,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pentanoic acid (1159408-54-4)

Guidance literature:

C₁₄H₂₅NO₈; With water; sodium hydroxide; In methanol;

acetic anhydride; With pyridine; at 30 ℃;

Reference yield: 71.0%

(2R,3R,4R,5R,6R)-5-acetamido-2-(acetoxymethyl)-6-(hex-5-en-1-yloxy)tetrahydro-2H-pyran-3,4-diyl diacetate → 5-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pentanoic acid (1159408-54-4)

Guidance literature:

(2R,3R,4R,5R,6R)-5-acetamido-2-(acetoxymethyl)-6-(hex-5-en-1-yloxy)tetrahydro-2H-pyran-3,4-diyl diacetate; With sodium periodate; In dichloromethane; water; acetonitrile; at 10 ℃; for 0.25h;

With ruthenium(II) chloride; at 20 - 35 ℃; for 1h;

DOI:10.1021/ja505986a

upstream raw materials:

2-amino-2-deoxy-α-D-galactopyranose hydrochloride

acetic acid (3aR,5R,6R,7R,7aR)-6-acetoxy-5-acetoxymethyl-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]oxazol-7-yl ester

3,4,5,6-tetrahydro-2H-pyran-2-one

methyl 5-hydroxypentanoate

Downstream raw materials:

C₅₄H₆₇N₅O₁₉

C₆₀H₈₁N₅O₁₉Si

C₆₀H₈₁N₅O₁₉Si