chlorure de (-)-aminocarbonyl-3-(hydroxymethyl-cis-4-dihydroxy-trans-2,3-cyclopentyl) 1-pyridinium

Base Information

• Chemical Name: chlorure de (-)-aminocarbonyl-3-(hydroxymethyl-cis-4-dihydroxy-trans-2,3-cyclopentyl) 1-pyridinium
• CAS No.: 102099-16-1
• Molecular Formula: C₁₂H₁₇N₂O₄*Cl
• Molecular Weight: 288.731
• Mol file: 102099-16-1.mol

Synonyms:

Chemical Property of chlorure de (-)-aminocarbonyl-3-(hydroxymethyl-cis-4-dihydroxy-trans-2,3-cyclopentyl) 1-pyridinium

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of chlorure de (-)-aminocarbonyl-3-(hydroxymethyl-cis-4-dihydroxy-trans-2,3-cyclopentyl) 1-pyridinium

There total 4 articles about chlorure de (-)-aminocarbonyl-3-(hydroxymethyl-cis-4-dihydroxy-trans-2,3-cyclopentyl) 1-pyridinium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

3-carbamoyl-1-(2,4-dinitrophenyl)pyridinium chloride (53406-00-1) + (-)-(1R,2R,3S,4R)-4-amino-2,3-dihydroxy-1-(hydroxymethyl)cyclopentane (85026-59-1,305384-32-1,780705-82-0) → chlorure de (-)-aminocarbonyl-3-(hydroxymethyl-cis-4-dihydroxy-trans-2,3-cyclopentyl) 1-pyridinium (102099-16-1,112344-69-1) + 2,4-Dinitroanilin (97-02-9)

Guidance literature:

In methanol; for 48h; Ambient temperature;

DOI:10.1016/0223-5234(89)90086-X

Reference yield:

3-carbamoyl-1-(2,4-dinitrophenyl)pyridinium chloride (53406-00-1) + (1β,2β,3α,5α)-5-Amino-3-hydroxymethyl-1,2-cyclopentanediol (106707-52-2,305384-32-1,780705-82-0) → chlorure de (+)-aminocarbonyl-3-(hydroxymethyl-cis-4-dihydroxy-trans-2,3-cyclopentyl) 1-pyridinium (102099-16-1,112344-69-1) + 2,4-Dinitroanilin (97-02-9)

Guidance literature:

In methanol; Ambient temperature;

DOI:10.1016/0223-5234(89)90086-X

Reference yield:

(1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxylmethyl)-1-aminocyclopentan hydrochloride (79200-57-0) + 1-(4,6-dimethoxy-triazine-2-yl)-3-carboxamidopyridinium chloride (1262957-26-5) → chlorure de (-)-aminocarbonyl-3-(hydroxymethyl-cis-4-dihydroxy-trans-2,3-cyclopentyl) 1-pyridinium (102099-16-1,112344-69-1)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In methanol; at 60 ℃; for 2h;

upstream raw materials:

3-carbamoyl-1-(2,4-dinitrophenyl)pyridinium chloride

(1β,2β,3α,5α)-5-Amino-3-hydroxymethyl-1,2-cyclopentanediol

(-)-(1R,2R,3S,4R)-4-amino-2,3-dihydroxy-1-(hydroxymethyl)cyclopentane

(1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxylmethyl)-1-aminocyclopentan hydrochloride

Downstream raw materials:

1-((1R,2S,3R,4R)-4-((((((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)hydroxyphosphoryl)oxy)oxidophosphoryl)oxy)methyl)-2,3-dihydroxycyclopentyl)-3-carbamoylpyridin-1-ium

Refernces

• 1、 Ikbal,Cerceau,Le Goffic,Sicsic. "Synthesis of the two enantiomers of the carbocyclic analog of nicotinamide ribose and analysis of their biological properties". . p. 415 - 420. Retrieved 2007/10/02.