1,18-diphenyloctadecane

Base Information

• Chemical Name: 1,18-diphenyloctadecane
• CAS No.: 24065-64-3
• Molecular Formula: C₃₀H₄₆
• Molecular Weight: 406.695
• Mol file: 24065-64-3.mol

Synonyms:

Chemical Property of 1,18-diphenyloctadecane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,18-diphenyloctadecane

There total 9 articles about 1,18-diphenyloctadecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-iodohexanoic acid (4224-63-9) → 1,18-diphenyloctadecane (24065-64-3)

Guidance literature:

Multi-step reaction with 5 steps

1: 25.3 g / methanol; diethyl ether

2: 1.) Mg, 2.) CuI, 1.5M CH₃Li / 1.) THF, 2.) THF, ether, -78 deg C, 1 h, -78 to 10 deg C, 3.) THF, ether, -78 deg C, 1 h, room temp., 20 h

3: 95 percent / LiAlH₄ / tetrahydrofuran

4: 83 percent / 48percent HBr, conc. H₂SO₄ / 3 h / Heating

5: 1.) Mg, 2.) CuI, 1.6M CH₃Li / 1.) THF, 2.) THF, ether, -78 deg C, 3.) THF, ether, -78 deg C

With copper(l) iodide; lithium aluminium tetrahydride; sulfuric acid; hydrogen bromide; methyllithium; magnesium; In tetrahydrofuran; methanol; diethyl ether;

DOI:10.3987/COM-95-7293

Reference yield:

methyl 6-iodohexanoate (14273-91-7) → 1,18-diphenyloctadecane (24065-64-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) Mg, 2.) CuI, 1.5M CH₃Li / 1.) THF, 2.) THF, ether, -78 deg C, 1 h, -78 to 10 deg C, 3.) THF, ether, -78 deg C, 1 h, room temp., 20 h

2: 95 percent / LiAlH₄ / tetrahydrofuran

3: 83 percent / 48percent HBr, conc. H₂SO₄ / 3 h / Heating

4: 1.) Mg, 2.) CuI, 1.6M CH₃Li / 1.) THF, 2.) THF, ether, -78 deg C, 3.) THF, ether, -78 deg C

With copper(l) iodide; lithium aluminium tetrahydride; sulfuric acid; hydrogen bromide; methyllithium; magnesium; In tetrahydrofuran;

DOI:10.3987/COM-95-7293

Reference yield:

9-phenylnonanoic acid methyl ester (24197-55-5) → 1,18-diphenyloctadecane (24065-64-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 95 percent / LiAlH₄ / tetrahydrofuran

2: 83 percent / 48percent HBr, conc. H₂SO₄ / 3 h / Heating

3: 1.) Mg, 2.) CuI, 1.6M CH₃Li / 1.) THF, 2.) THF, ether, -78 deg C, 3.) THF, ether, -78 deg C

With copper(l) iodide; lithium aluminium tetrahydride; sulfuric acid; hydrogen bromide; methyllithium; magnesium; In tetrahydrofuran;

DOI:10.3987/COM-95-7293

upstream raw materials:

1,12-dibromododecane

3-phenylpropylmagnesium bromide

9-phenyl-1-bromononane

succinic acid monomethylester chloride