3-Oxo-5-phenylsulfinylpentansaeuremethylester

Base Information

• Chemical Name: 3-Oxo-5-phenylsulfinylpentansaeuremethylester
• CAS No.: 51849-24-2
• Molecular Formula: C₁₂H₁₄O₄S
• Molecular Weight: 254.307
• Mol file: 51849-24-2.mol

Synonyms:

Chemical Property of 3-Oxo-5-phenylsulfinylpentansaeuremethylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Oxo-5-phenylsulfinylpentansaeuremethylester

There total 3 articles about 3-Oxo-5-phenylsulfinylpentansaeuremethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 3-oxo-5-(phenylthio)pentanoate (51849-20-8) → 3-Oxo-5-phenylsulfinylpentansaeuremethylester (51849-24-2)

Guidance literature:

With sodium periodate; In methanol;

DOI:10.1021/jo00931a052

Reference yield:

phenylthiomethyl chloride (7205-91-6) → 3-Oxo-5-phenylsulfinylpentansaeuremethylester (51849-24-2)

Guidance literature:

Multi-step reaction with 3 steps

1: NaI / acetone

2: (i) NaH, (ii) nBuLi, (iii) /BRN= 1931495/

3: aq. NaIO₄ / methanol

With sodium periodate; sodium iodide; In methanol; acetone;

DOI:10.1021/jo00931a052

Reference yield:

iodomethyl phenyl sulfide (51849-22-0) → 3-Oxo-5-phenylsulfinylpentansaeuremethylester (51849-24-2)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) NaH, (ii) nBuLi, (iii) /BRN= 1931495/

2: aq. NaIO₄ / methanol

With sodium periodate; In methanol;

DOI:10.1021/jo00931a052

upstream raw materials:

methyl 3-oxo-5-(phenylthio)pentanoate

phenylthiomethyl chloride

iodomethyl phenyl sulfide

Downstream raw materials:

5-Benzenesulfinyl-2-[1-methyl-pyrrolidin-(2E)-ylidene]-3-oxo-pentanoic acid methyl ester