4-acetyl-4-phenyl-heptanedioic acid diamide

Base Information

• Chemical Name: 4-acetyl-4-phenyl-heptanedioic acid diamide
• CAS No.: 411220-55-8
• Molecular Formula: C₁₅H₂₀N₂O₃
• Molecular Weight: 276.335
• Mol file: 411220-55-8.mol

Synonyms:

Chemical Property of 4-acetyl-4-phenyl-heptanedioic acid diamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-acetyl-4-phenyl-heptanedioic acid diamide

There total 1 articles about 4-acetyl-4-phenyl-heptanedioic acid diamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-acetyl-3-phenyl-1,5-pentanedicarboxylic acid (68756-11-6) → 4-acetyl-4-phenyl-heptanedioic acid diamide (411220-55-8)

Guidance literature:

With thionyl chloride; anschliessend Behandeln mit wss. NH₃;

DOI:10.1021/ja01157a092

Reference yield:

4-acetyl-4-phenyl-heptanedioic acid diamide (411220-55-8) → 4a-phenyl-4,4a,5,6-tetrahydro-1H,3H-quinoline-2,7-dione (1216-47-3)

Guidance literature:

With sulfuric acid; water;

DOI:10.1021/ja01157a092

Reference yield:

4-acetyl-4-phenyl-heptanedioic acid diamide (411220-55-8) → 7-hydroxy-4a-phenyl-octahydro-quinolin-2-one (101104-86-3)

Guidance literature:

Multi-step reaction with 2 steps

1: water; sulfuric acid

2: Raney nickel; ethanol / 165 °C / 51485.6 Torr / Hydrogenation

With ethanol; sulfuric acid; water; nickel;

DOI:10.1021/ja01157a092

upstream raw materials:

3-acetyl-3-phenyl-1,5-pentanedicarboxylic acid

Downstream raw materials:

4a-phenyl-4,4a,5,6-tetrahydro-1H,3H-quinoline-2,7-dione

7-hydroxy-4a-phenyl-octahydro-quinolin-2-one