Phosphoric acid (2R,3R,4R,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 5-chloro-quinolin-8-yl ester; compound with pyridine

Base Information

Chemical Name:Phosphoric acid (2R,3R,4R,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 5-chloro-quinolin-8-yl ester; compound with pyridine
CAS No.:78462-59-6
Molecular Formula:C₅H₅N*C₅₂H₄₈ClN₆O₁₁P
Molecular Weight:1078.51
Hs Code.:

Phosphoric acid (2R,3R,4R,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 5-chloro-quinolin-8-yl ester; compound with pyridine

Synonyms:

Suppliers and Price of Phosphoric acid (2R,3R,4R,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 5-chloro-quinolin-8-yl ester; compound with pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Phosphoric acid (2R,3R,4R,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 5-chloro-quinolin-8-yl ester; compound with pyridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Phosphoric acid (2R,3R,4R,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 5-chloro-quinolin-8-yl ester; compound with pyridine

There total 4 articles about Phosphoric acid (2R,3R,4R,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 5-chloro-quinolin-8-yl ester; compound with pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 75933-80-1
5'-O-(dimethoxytrityl)-2'-O-(tetrahydropyranyl)-N⁶-benzoyladenosine-3'-(4-chlorophenyl 5-chloro-8-quinolyl-phosphate)

: 78462-59-6
Phosphoric acid (2R,3R,4R,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 5-chloro-quinolin-8-yl ester; compound with pyridine

Guidance literature:: With N₁,N₁,N₃,N₃-tetrametylquanidium salt of 2-pyridinecarboxaldehyde oxim; In 1,4-dioxane; water; at 20 ℃; for 16h; Yield given;
DOI:10.1246/cl.1981.197

Reference yield:

: 75933-80-1
5'-O-(dimethoxytrityl)-2'-O-(tetrahydropyranyl)-N⁶-benzoyladenosine-3'-(4-chlorophenyl 5-chloro-8-quinolyl-phosphate)

: 78462-59-6
Phosphoric acid (2R,3R,4R,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 5-chloro-quinolin-8-yl ester; compound with pyridine

Guidance literature:: With N₁,N₁,N₃,N₃-tetrametylquanidium salt of 2-pyridinecarboxaldehyde oxim; In 1,4-dioxane; methanol; at 20 ℃; for 16h; Yield given;
DOI:10.1246/cl.1981.543

Reference yield:

: 71933-61-4
5'-O-(dimethoxytrityl)-2'-O-(tetrahydropyranyl)-N⁶-benzoyladenosine

: 78462-59-6
Phosphoric acid (2R,3R,4R,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 5-chloro-quinolin-8-yl ester; compound with pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) triethylamine, 2.) 1-methylimidazole (1-MeIm) / 1.) THF, -10 - -20 deg C, 0.75 h, 2.) room temperature, 1 h

2: 1 M N¹,N¹,N³,N³-tetramethylguanidium salt of 2-pyridinaldoxime / dioxane; H₂O / 16 h / 20 °C

With 1-methyl-1H-imidazole; N₁,N₁,N₃,N₃-tetrametylquanidium salt of 2-pyridinecarboxaldehyde oxim; triethylamine; In 1,4-dioxane; water;
DOI:10.1246/cl.1981.197