1-(2-Nitrophenyl)-2-pyridin-2-ylmethanol

Base Information

• Chemical Name: 1-(2-Nitrophenyl)-2-pyridin-2-ylmethanol
• CAS No.: 5455-70-9
• Molecular Formula: C₁₃H₁₂N₂O₃
• Molecular Weight: 244.25
• Hs Code.: 2933399090
• NSC Number: 23439
• ChEMBL ID: CHEMBL2137489
• Mol file: 5455-70-9.mol

Synonyms:5455-70-9;1-(2-nitrophenyl)-2-pyridin-2-ylmethanol;MLS002638943;NSC23439;CHEMBL2137489;HMS3093G20;NSC-23439;SMR001548403

Chemical Property of 1-(2-Nitrophenyl)-2-pyridin-2-ylmethanol

Chemical Property:

• Vapor Pressure: 1.07E-07mmHg at 25°C
• Boiling Point: 416.9°Cat760mmHg
• Flash Point: 205.9°C
• PSA: 78.94000
• Density: 1.311g/cm³
• LogP: 2.78910
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 244.08479225
• Heavy Atom Count: 18
• Complexity: 280

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)C(CC2=CC=CC=N2)O)[N+](=O)[O-]

Technology Process of 1-(2-Nitrophenyl)-2-pyridin-2-ylmethanol

There total 2 articles about 1-(2-Nitrophenyl)-2-pyridin-2-ylmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

α-picoline (109-06-8) + 2-nitro-benzaldehyde (552-89-6) → 1-(2-nitro-phenyl)-2-[2]pyridyl-ethanol (5455-70-9)

Guidance literature:

With water; at 137 - 140 ℃;

Reference yield:

→ 1-(2-nitro-phenyl)-2-[2]pyridyl-ethanol (5455-70-9)

Guidance literature:

With nitric acid;

Reference yield:

1-(2-nitro-phenyl)-2-[2]pyridyl-ethanol (5455-70-9) → 2-(2-pyridin-2-yl-ethyl)-aniline (50385-28-9)

Guidance literature:

With phosphorus; hydrogen iodide; at 160 ℃;

DOI:10.1039/jr9490003172

upstream raw materials:

α-picoline

2-nitro-benzaldehyde

Downstream raw materials:

2-(2-pyridin-2-yl-ethyl)-aniline

2-<β-(4'-Hydroxyphenyl)-ethyl>-pyridin

2-(2-chloro-phenethyl)-pyridine

3,3-dimethyl-1-[2-(2-[2]pyridyl-ethyl)-phenyl]-triazene