3-[2-(Benzylamino)ethoxy]phenol

Base Information

Chemical Name:3-[2-(Benzylamino)ethoxy]phenol
CAS No.:129689-29-8
Molecular Formula:C₁₅H₁₇NO₂
Molecular Weight:243.305
Hs Code.:
ChEMBL ID:CHEMBL64508
DSSTox Substance ID:DTXSID701280854
Nikkaji Number:J1.120.480E
Pharos Ligand ID:7LQTQC65FVMT

Synonyms:3-(2-(benzylamino)ethoxy)phenol;3-OHPheOEAB

Suppliers and Price of 3-[2-(Benzylamino)ethoxy]phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3-[2-(Benzylamino)ethoxy]phenol

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:243.125928785
Heavy Atom Count:18
Complexity:217

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)CNCCOC2=CC=CC(=C2)O

Technology Process of 3-[2-(Benzylamino)ethoxy]phenol

There total 4 articles about 3-[2-(Benzylamino)ethoxy]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 204122-20-3
tert-butyl benzyl(2-(3-methoxyphenoxy)ethyl)carbamate

: 129689-29-8
N-benzyl-2-(3-hydroxyphenoxy)ethylamine

Guidance literature:: With hydrogen bromide;
DOI:10.1016/S0960-894X(98)00014-6

Reference yield:

: 107332-83-2
3-(2-bromoethoxy)phenol

: 100-46-9
benzylamine

: 129689-29-8
N-benzyl-2-(3-hydroxyphenoxy)ethylamine

Guidance literature:: With triethylamine; In ethanol; for 60h; Heating;
DOI:10.1021/jm00088a010

Reference yield:

: 121496-39-7
N-(tert-butoxycarbonyl)-N-benzylethanolamine

: 129689-29-8
N-benzyl-2-(3-hydroxyphenoxy)ethylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / DIAD, PPh₃ / tetrahydrofuran

2: 30 percent / 48percent aq. HBr

With di-isopropyl azodicarboxylate; hydrogen bromide; triphenylphosphine; In tetrahydrofuran;
DOI:10.1016/S0960-894X(98)00014-6