Technology Process of C18H17N7O2
There total 4 articles about C18H17N7O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium azide; ; L-proline; sodium L-ascorbate; sodium carbonate / water; dimethyl sulfoxide / 0.5 h / 130 °C / Microwave irradiation
2: ammonia / water; dimethyl sulfoxide / 2 h
With
sodium azide; ammonia; sodium carbonate; sodium L-ascorbate; L-proline;
In
water; dimethyl sulfoxide;
DOI:10.1039/c4ob00904e
- Guidance literature:
-
Multi-step reaction with 5 steps
1: N,N-dimethyl-formamide / 18 h / 60 °C / Sealed tube; Inert atmosphere
2: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / N,N-dimethyl-formamide / 18 h / 20 °C / Sealed tube; Inert atmosphere
3: Amberlite? IRA 900 F-form / chloroform / 18 h / 20 °C / Inert atmosphere
4: sodium azide; ; L-proline; sodium L-ascorbate; sodium carbonate / water; dimethyl sulfoxide / 0.5 h / 130 °C / Microwave irradiation
5: ammonia / water; dimethyl sulfoxide / 2 h
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; sodium azide; ammonia; sodium carbonate; sodium L-ascorbate; triethylamine; L-proline;
In
chloroform; water; dimethyl sulfoxide; N,N-dimethyl-formamide;
2: |Sonogashira Cross-Coupling;
DOI:10.1039/c4ob00904e
- Guidance literature:
-
Multi-step reaction with 6 steps
1: caesium carbonate / N,N-dimethyl-formamide / 18 h / 0 - 20 °C / Sealed tube; Inert atmosphere
2: N,N-dimethyl-formamide / 18 h / 60 °C / Sealed tube; Inert atmosphere
3: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / N,N-dimethyl-formamide / 18 h / 20 °C / Sealed tube; Inert atmosphere
4: Amberlite? IRA 900 F-form / chloroform / 18 h / 20 °C / Inert atmosphere
5: sodium azide; ; L-proline; sodium L-ascorbate; sodium carbonate / water; dimethyl sulfoxide / 0.5 h / 130 °C / Microwave irradiation
6: ammonia / water; dimethyl sulfoxide / 2 h
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; sodium azide; ammonia; sodium carbonate; caesium carbonate; sodium L-ascorbate; triethylamine; L-proline;
In
chloroform; water; dimethyl sulfoxide; N,N-dimethyl-formamide;
3: |Sonogashira Cross-Coupling;
DOI:10.1039/c4ob00904e