4-[4-(2-Chloro-benzyloxy)-phenyl]-thiazol-2-ylamine; hydrobromide

Base Information

Chemical Name:4-[4-(2-Chloro-benzyloxy)-phenyl]-thiazol-2-ylamine; hydrobromide
CAS No.:79040-24-7
Molecular Formula:BrH*C₁₆H₁₃ClN₂OS
Molecular Weight:397.723
Hs Code.:

Synonyms:

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Chemical Property of 4-[4-(2-Chloro-benzyloxy)-phenyl]-thiazol-2-ylamine; hydrobromide

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Technology Process of 4-[4-(2-Chloro-benzyloxy)-phenyl]-thiazol-2-ylamine; hydrobromide

There total 4 articles about 4-[4-(2-Chloro-benzyloxy)-phenyl]-thiazol-2-ylamine; hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.9%

: 79615-92-2
2-Bromo-1-[4-(2-chloro-benzyloxy)-phenyl]-ethanone

: 17356-08-0
thiourea

: 79040-24-7
4-[4-(2-Chloro-benzyloxy)-phenyl]-thiazol-2-ylamine; hydrobromide

Guidance literature:: In ethanol; for 1h; Heating;

Reference yield:

: 72293-95-9
1-(4-((2-chlorobenzyl)oxy)phenyl)ethanone

: 79040-24-7
4-[4-(2-Chloro-benzyloxy)-phenyl]-thiazol-2-ylamine; hydrobromide

Guidance literature:: Multi-step reaction with 2 steps

1: 65.1 percent / pyridinium hydrobromide perbromide / acetic acid / 1 h / 50 °C

2: 73.9 percent / ethanol / 1 h / Heating

With pyridinium hydrobromide perbromide; In ethanol; acetic acid;

Reference yield:

: 611-19-8
1-chloro-2-(chloromethyl)benzene

: 79040-24-7
4-[4-(2-Chloro-benzyloxy)-phenyl]-thiazol-2-ylamine; hydrobromide

Guidance literature:: Multi-step reaction with 3 steps

1: 87.2 percent / K₂CO₃ / dimethylformamide / 3 h / 90 °C

2: 65.1 percent / pyridinium hydrobromide perbromide / acetic acid / 1 h / 50 °C

3: 73.9 percent / ethanol / 1 h / Heating

With pyridinium hydrobromide perbromide; potassium carbonate; In ethanol; acetic acid; N,N-dimethyl-formamide;