N-(2-chloro-2-phenylethyl)isopropylammonium chloride

Base Information

Chemical Name:N-(2-chloro-2-phenylethyl)isopropylammonium chloride
CAS No.:1078-35-9
Molecular Formula:C₁₁H₁₆ClN*ClH
Molecular Weight:234.169
Hs Code.:

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Chemical Property of N-(2-chloro-2-phenylethyl)isopropylammonium chloride

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Technology Process of N-(2-chloro-2-phenylethyl)isopropylammonium chloride

There total 2 articles about N-(2-chloro-2-phenylethyl)isopropylammonium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 4164-21-0,14467-49-3,14467-53-9,28148-83-6
2-(isopropylamino)-1-phenylethanol

: 1078-35-9
N-(2-chloro-2-phenylethyl)isopropylammonium chloride

Guidance literature:: With thionyl chloride; In dichloromethane; for 12h; Reflux;
DOI:10.1021/om2008919

Reference yield:

: 96-09-3
styrene oxide

: 1078-35-9
N-(2-chloro-2-phenylethyl)isopropylammonium chloride

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 48 h / Reflux; Inert atmosphere

2: thionyl chloride / dichloromethane / 12 h / Reflux

With thionyl chloride; In ethanol; dichloromethane;
DOI:10.1021/om2008919

Reference yield: 80.0%

: 1078-35-9
N-(2-chloro-2-phenylethyl)isopropylammonium chloride

: 1242514-70-0
((2-naphthyl)isocyano)gold(I) chloride

: [1-((2-naphthyl)amino)-5-(isopropylamino)-2-phenylimidazolidene]gold(I) chloride

Guidance literature:: With Et₃N; In dichloromethane; Au complex reacted with ammonium salt in presence of Et3N in CH2Cl2 at room temp. for 48 h; according to A. S. K. Hashmi et al., Adv. Synth. Catal., 2010, 352, 3001; purified by column chromy. (silica, CH2Cl2);
DOI:10.1021/om2008919