C₂₁⁽¹³⁾CH₂₁P

Base Information

• Chemical Name: C₂₁⁽¹³⁾CH₂₁P
• CAS No.: 90929-04-7
• Molecular Formula: C₂₂H₂₁P
• Molecular Weight: 317.371
• Mol file: 90929-04-7.mol

Synonyms:

Chemical Property of C₂₁⁽¹³⁾CH₂₁P

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of C₂₁⁽¹³⁾CH₂₁P

There total 11 articles about C₂₁⁽¹³⁾CH₂₁P which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

benzophenone (32488-48-5) + lithium mesityl(trimetylsilyl)phosphide (79908-17-1) → C21(13)CH21P (90929-04-7)

Guidance literature:

In tetrahydrofuran; at -78 ℃; Inert atmosphere;

DOI:10.1002/anie.201301881

Reference yield:

2,4,6-trimethylphenyl bromide (576-83-0) → C21(13)CH21P (90929-04-7)

Guidance literature:

Multi-step reaction with 5 steps

1: 1.) Mg / 1.) THF, 2.) THF, -40 deg C to -50 deg C, 1.5h

2: 49 percent / 1.68N HCl / diethyl ether

3: 1.) 1.5N n-butyllithium / 1.)THF, hexane, 2.) RT, 20h

4: 2.14N HCl / tetrahydrofuran; diethyl ether

5: DBU / tetrahydrofuran / 1.) RT, 2.5h, 2.) 20h

With hydrogenchloride; n-butyllithium; magnesium; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; diethyl ether;

DOI:10.1016/S0040-4020(01)91106-8

Reference yield:

C21(13)CH22ClP (90929-06-9) → C21(13)CH21P (90929-04-7)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; 1.) RT, 2.5h, 2.) 20h;

DOI:10.1016/S0040-4020(01)91106-8

upstream raw materials:

C₂₁⁽¹³⁾CH₂₂ClP

2,4,6-trimethylphenyl bromide

<1-13C>-Diphenylmethan

1-(13C)benzoic acid