Technology Process of 8-Benzyloxy-4,4a,5,6,11,11b-hexahydro-1H,3H-pyrido[3,4-a]carbazole-2-carboxylic acid ethyl ester
There total 4 articles about 8-Benzyloxy-4,4a,5,6,11,11b-hexahydro-1H,3H-pyrido[3,4-a]carbazole-2-carboxylic acid ethyl ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 91 percent / CrO3, conc H2SO4 / H2O; acetone
2: 67 percent / KOH / methanol; H2O / 6 h / Heating
3: 76 percent / pyridine / 24 h / ice-cooling
4: 1.) AcOH, 2.) NaOAc / 1.) EtOH, reflux, 10 min; 2.) AcOH, 70-75 deg C, 24 h
With
chromium(VI) oxide; potassium hydroxide; sulfuric acid; sodium acetate; acetic acid;
In
pyridine; methanol; water; acetone;
DOI:10.1016/S0040-4020(01)96570-6
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 67 percent / KOH / methanol; H2O / 6 h / Heating
2: 76 percent / pyridine / 24 h / ice-cooling
3: 1.) AcOH, 2.) NaOAc / 1.) EtOH, reflux, 10 min; 2.) AcOH, 70-75 deg C, 24 h
With
potassium hydroxide; sodium acetate; acetic acid;
In
pyridine; methanol; water;
DOI:10.1016/S0040-4020(01)96570-6
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 76 percent / pyridine / 24 h / ice-cooling
2: 1.) AcOH, 2.) NaOAc / 1.) EtOH, reflux, 10 min; 2.) AcOH, 70-75 deg C, 24 h
With
sodium acetate; acetic acid;
In
pyridine;
DOI:10.1016/S0040-4020(01)96570-6
