(3S,4R,4aR,6S,6aS,12aR,12bS)-9-(3,4-Dimethoxy-phenyl)-4,6a,12b-trimethyl-3,6-bis-trimethylsilanyloxy-4-trimethylsilanyloxymethyl-1,2,3,4,4a,5,6,6a,12a,12b-decahydro-7,10-dioxa-benzo[a]anthracene-11,12-dione

Base Information

Chemical Name:(3S,4R,4aR,6S,6aS,12aR,12bS)-9-(3,4-Dimethoxy-phenyl)-4,6a,12b-trimethyl-3,6-bis-trimethylsilanyloxy-4-trimethylsilanyloxymethyl-1,2,3,4,4a,5,6,6a,12a,12b-decahydro-7,10-dioxa-benzo[a]anthracene-11,12-dione
CAS No.:195527-12-9
Molecular Formula:C₃₇H₅₈O₉Si₃
Molecular Weight:731.119
Hs Code.:

(3S,4R,4aR,6S,6aS,12aR,12bS)-9-(3,4-Dimethoxy-phenyl)-4,6a,12b-trimethyl-3,6-bis-trimethylsilanyloxy-4-trimethylsilanyloxymethyl-1,2,3,4,4a,5,6,6a,12a,12b-decahydro-7,10-dioxa-benzo[a]anthracene-11,12-dione

Synonyms:

Suppliers and Price of (3S,4R,4aR,6S,6aS,12aR,12bS)-9-(3,4-Dimethoxy-phenyl)-4,6a,12b-trimethyl-3,6-bis-trimethylsilanyloxy-4-trimethylsilanyloxymethyl-1,2,3,4,4a,5,6,6a,12a,12b-decahydro-7,10-dioxa-benzo[a]anthracene-11,12-dione

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (3S,4R,4aR,6S,6aS,12aR,12bS)-9-(3,4-Dimethoxy-phenyl)-4,6a,12b-trimethyl-3,6-bis-trimethylsilanyloxy-4-trimethylsilanyloxymethyl-1,2,3,4,4a,5,6,6a,12a,12b-decahydro-7,10-dioxa-benzo[a]anthracene-11,12-dione

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Hazard Codes:

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Useful:

Technology Process of (3S,4R,4aR,6S,6aS,12aR,12bS)-9-(3,4-Dimethoxy-phenyl)-4,6a,12b-trimethyl-3,6-bis-trimethylsilanyloxy-4-trimethylsilanyloxymethyl-1,2,3,4,4a,5,6,6a,12a,12b-decahydro-7,10-dioxa-benzo[a]anthracene-11,12-dione

There total 4 articles about (3S,4R,4aR,6S,6aS,12aR,12bS)-9-(3,4-Dimethoxy-phenyl)-4,6a,12b-trimethyl-3,6-bis-trimethylsilanyloxy-4-trimethylsilanyloxymethyl-1,2,3,4,4a,5,6,6a,12a,12b-decahydro-7,10-dioxa-benzo[a]anthracene-11,12-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 171925-86-3
Acetic acid (3S,4R,4aR,6S,6aS,12aR,12bS)-3-acetoxy-4-acetoxymethyl-4,6a,12b-trimethyl-11,12-dioxo-9-pyridin-3-yl-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-2H,11H-7,10-dioxa-benzo[a]anthracen-6-yl ester

: 195527-12-9
(3S,4R,4aR,6S,6aS,12aR,12bS)-9-(3,4-Dimethoxy-phenyl)-4,6a,12b-trimethyl-3,6-bis-trimethylsilanyloxy-4-trimethylsilanyloxymethyl-1,2,3,4,4a,5,6,6a,12a,12b-decahydro-7,10-dioxa-benzo[a]anthracene-11,12-dione

Guidance literature:: Multi-step reaction with 4 steps

1: 80 percent / MeONa / H₂O / 17 h / Ambient temperature

2: 90 percent / 2,6-lutidine / CH₂Cl₂ / 0.33 h / Ambient temperature

3: 1.) LiHMDS, TMEDA / tetrahydrofuran / 1.) 0 deg C, 0.5 h, then room temp., 1.5 h; 2.) 0 deg C

4: tetrahydrofuran / 0 deg C, 0.5 h, then room temp., 1.5 h

With 2,6-dimethylpyridine; N,N,N,N,-tetramethylethylenediamine; sodium methylate; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane; water;
DOI:10.1246/cl.1997.935

Reference yield:

: 172704-62-0
(4aS,5S,6aR,7R,8S,10aS,10bR)-5,8-Dihydroxy-7-hydroxymethyl-3,4a,7,10a-tetramethyl-1-oxo-4a,5,6,6a,7,8,9,10,10a,10b-decahydro-1H-benzo[f]chromene-2-carboxylic acid methyl ester

: 195527-12-9
(3S,4R,4aR,6S,6aS,12aR,12bS)-9-(3,4-Dimethoxy-phenyl)-4,6a,12b-trimethyl-3,6-bis-trimethylsilanyloxy-4-trimethylsilanyloxymethyl-1,2,3,4,4a,5,6,6a,12a,12b-decahydro-7,10-dioxa-benzo[a]anthracene-11,12-dione

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / 2,6-lutidine / CH₂Cl₂ / 0.33 h / Ambient temperature

2: 1.) LiHMDS, TMEDA / tetrahydrofuran / 1.) 0 deg C, 0.5 h, then room temp., 1.5 h; 2.) 0 deg C

3: tetrahydrofuran / 0 deg C, 0.5 h, then room temp., 1.5 h

With 2,6-dimethylpyridine; N,N,N,N,-tetramethylethylenediamine; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane;
DOI:10.1246/cl.1997.935

Reference yield:

: 189564-01-0
(4aS,5S,6aR,7R,8S,10aS,10bR)-3,4a,7,10a-Tetramethyl-1-oxo-5,8-bis-trimethylsilanyloxy-7-trimethylsilanyloxymethyl-4a,5,6,6a,7,8,9,10,10a,10b-decahydro-1H-benzo[f]chromene-2-carboxylic acid methyl ester

: 195527-12-9
(3S,4R,4aR,6S,6aS,12aR,12bS)-9-(3,4-Dimethoxy-phenyl)-4,6a,12b-trimethyl-3,6-bis-trimethylsilanyloxy-4-trimethylsilanyloxymethyl-1,2,3,4,4a,5,6,6a,12a,12b-decahydro-7,10-dioxa-benzo[a]anthracene-11,12-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) LiHMDS, TMEDA / tetrahydrofuran / 1.) 0 deg C, 0.5 h, then room temp., 1.5 h; 2.) 0 deg C

2: tetrahydrofuran / 0 deg C, 0.5 h, then room temp., 1.5 h

With N,N,N,N,-tetramethylethylenediamine; lithium hexamethyldisilazane; In tetrahydrofuran;
DOI:10.1246/cl.1997.935