Technology Process of C56H72N2O3
There total 4 articles about C56H72N2O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid;
In
methanol;
DOI:10.1021/ja4004816
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: N,N,N,N,-tetramethylethylenediamine; n-butyllithium / tetrahydrofuran / 4 h / Schlenk technique; Glovebox; Cooling
1.2: 10 h / Schlenk technique; Glovebox; Cooling
2.1: hydrogenchloride / water; methanol / 2 h / Reflux
3.1: toluene-4-sulfonic acid / methanol
With
hydrogenchloride; n-butyllithium; N,N,N,N,-tetramethylethylenediamine; toluene-4-sulfonic acid;
In
tetrahydrofuran; methanol; water;
DOI:10.1021/ja4004816
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: tert.-butyl lithium / tetrahydrofuran / 1 h / 20 °C / Schlenk technique; Glovebox; Cooling
1.2: 1 h / Cooling; Schlenk technique; Glovebox
1.3: 96 h / 70 °C / Schlenk technique; Glovebox; Sealed tube
2.1: N,N,N,N,-tetramethylethylenediamine; n-butyllithium / tetrahydrofuran / 4 h / Schlenk technique; Glovebox; Cooling
2.2: 10 h / Schlenk technique; Glovebox; Cooling
3.1: hydrogenchloride / water; methanol / 2 h / Reflux
4.1: toluene-4-sulfonic acid / methanol
With
hydrogenchloride; n-butyllithium; N,N,N,N,-tetramethylethylenediamine; tert.-butyl lithium; toluene-4-sulfonic acid;
In
tetrahydrofuran; methanol; water;
1.3: |Negishi Coupling;
DOI:10.1021/ja4004816
