2-isobutyl-1,4-butanediol

Base Information

• Chemical Name: 2-isobutyl-1,4-butanediol
• CAS No.: 90951-75-0
• Molecular Formula: C₈H₁₈O₂
• Molecular Weight: 146.23
• Mol file: 90951-75-0.mol

Synonyms:

Chemical Property of 2-isobutyl-1,4-butanediol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-isobutyl-1,4-butanediol

There total 1 articles about 2-isobutyl-1,4-butanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Methyl-1-pentene (691-37-2,25068-26-2) + triethylaluminum (97-93-8) → 2-isobutyl-1,4-butanediol (90951-75-0) + (2S)-ethyl-4-methyl-1-pentanol (56640-33-6,111767-90-9) + (2R)-ethyl-4-methyl-1-pentanol (111767-90-9)

Guidance literature:

4-Methyl-1-pentene; triethylaluminum; With bis(1-(-)-neomenthylindenyl)zirconium dichloride; In dichloromethane; at 20 - 25 ℃; for 24h; Inert atmosphere; Schlenk technique;

With oxygen; In dichloromethane; at 0 ℃; for 26h; enantioselective reaction;

DOI:10.1016/j.tetasy.2014.11.019

Reference yield:

2-isobutyl-1,4-butanediol (90951-75-0) → benzyl 3-isobutylpyrrolidine-1-carboxylate

Guidance literature:

Multi-step reaction with 2 steps

1: bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; cesium bicarbonate; cyclopentyl methyl ether / 24 h / 110 °C / Microwave irradiation; Inert atmosphere; Sealed tube

2: toluene / 2 h / 80 °C / Inert atmosphere; Microwave irradiation; Sealed tube

With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; cesium bicarbonate; cyclopentyl methyl ether; In toluene;

DOI:10.1039/d0cc00903b

Reference yield:

2-isobutyl-1,4-butanediol (90951-75-0) + benzylamine (100-46-9) → 1-benzyl-3-isobutylpyrrolidine

Guidance literature:

With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; cesium bicarbonate; cyclopentyl methyl ether; at 110 ℃; for 24h; Microwave irradiation; Inert atmosphere; Sealed tube;

DOI:10.1039/d0cc00903b

upstream raw materials:

4-Methyl-1-pentene

triethylaluminum