Technology Process of 4-(4-methylphenyl)-2-phenylbenzo[b]furan
There total 3 articles about 4-(4-methylphenyl)-2-phenylbenzo[b]furan which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: dichloro bis(acetonitrile) palladium(II); C31H36O2*BF4(1-)*H(1+); lithium tert-butoxide; XPhos / toluene / 0.25 h / 20 °C / Inert atmosphere
1.2: 0.75 h / Inert atmosphere; Reflux
1.3: 2 h / Inert atmosphere; Reflux
2.1: potassium phosphate / toluene; water / 6 h / Inert atmosphere; Reflux
With
dichloro bis(acetonitrile) palladium(II); potassium phosphate; C31H36O2*BF4(1-)*H(1+); lithium tert-butoxide; XPhos;
In
water; toluene;
1.1: |Sonogashira Cross-Coupling / 2.1: |Suzuki-Miyaura Coupling;
DOI:10.1021/jo401503t
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: dichloro bis(acetonitrile) palladium(II); C31H36O2*BF4(1-)*H(1+); lithium tert-butoxide; XPhos / toluene / 0.25 h / 20 °C / Inert atmosphere
1.2: 0.75 h / Inert atmosphere; Reflux
1.3: 2 h / Inert atmosphere; Reflux
2.1: potassium phosphate / toluene; water / 6 h / Inert atmosphere; Reflux
With
dichloro bis(acetonitrile) palladium(II); potassium phosphate; C31H36O2*BF4(1-)*H(1+); lithium tert-butoxide; XPhos;
In
water; toluene;
1.1: |Sonogashira Cross-Coupling / 2.1: |Suzuki-Miyaura Coupling;
DOI:10.1021/jo401503t
- Guidance literature:
-
With
potassium phosphate;
In
water; toluene;
for 6h;
Inert atmosphere;
Reflux;
DOI:10.1021/jo401503t
