(R)-2-{[(S)-1-[(S)-1-((R)-1-Aminomethyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-2-(1H-indol-3-yl)-ethylcarbamoyl]-methyl}-succinic acid 4-tert-butyl ester

Base Information

Chemical Name:(R)-2-{[(S)-1-[(S)-1-((R)-1-Aminomethyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-2-(1H-indol-3-yl)-ethylcarbamoyl]-methyl}-succinic acid 4-tert-butyl ester
CAS No.:437985-39-2
Molecular Formula:C₃₉H₄₇N₅O₇
Molecular Weight:697.831
Hs Code.:

(R)-2-{[(S)-1-[(S)-1-((R)-1-Aminomethyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-2-(1H-indol-3-yl)-ethylcarbamoyl]-methyl}-succinic acid 4-tert-butyl ester

Synonyms:

Suppliers and Price of (R)-2-{[(S)-1-[(S)-1-((R)-1-Aminomethyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-2-(1H-indol-3-yl)-ethylcarbamoyl]-methyl}-succinic acid 4-tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-2-{[(S)-1-[(S)-1-((R)-1-Aminomethyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-2-(1H-indol-3-yl)-ethylcarbamoyl]-methyl}-succinic acid 4-tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-2-{[(S)-1-[(S)-1-((R)-1-Aminomethyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-2-(1H-indol-3-yl)-ethylcarbamoyl]-methyl}-succinic acid 4-tert-butyl ester

There total 4 articles about (R)-2-{[(S)-1-[(S)-1-((R)-1-Aminomethyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-2-(1H-indol-3-yl)-ethylcarbamoyl]-methyl}-succinic acid 4-tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (R)-2-{[(S)-1-{(S)-1-[(R)-1-(Benzyloxycarbonylamino-methyl)-2-phenyl-ethylcarbamoyl]-2-phenyl-ethylcarbamoyl}-2-(1H-indol-3-yl)-ethylcarbamoyl]-methyl}-succinic acid 1-benzyl ester 4-tert-butyl ester

: 437985-39-2
(R)-2-{[(S)-1-[(S)-1-((R)-1-Aminomethyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-2-(1H-indol-3-yl)-ethylcarbamoyl]-methyl}-succinic acid 4-tert-butyl ester

Guidance literature:: With palladium on activated charcoal; hydrogen; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(01)00841-1

Reference yield:

: 264144-34-5
3(R)-benzyloxycarbonylpentanedioic acid mono-tert-butyl ester

: 437985-39-2
(R)-2-{[(S)-1-[(S)-1-((R)-1-Aminomethyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-2-(1H-indol-3-yl)-ethylcarbamoyl]-methyl}-succinic acid 4-tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: EDC*HCl; HOBt / dimethylformamide

2: H₂; Pd/C / methanol; dimethylformamide

With palladium on activated charcoal; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(01)00841-1

Reference yield:

: 211689-64-4
(2-(R)-{2-(S)-[2-(S)-amino-3-(1H-indol-3-yl)propionylamino]-3-phenylpropionylamino}-3-phenylpropyl)carbamic acid benzyl ester

: 437985-39-2
(R)-2-{[(S)-1-[(S)-1-((R)-1-Aminomethyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-2-(1H-indol-3-yl)-ethylcarbamoyl]-methyl}-succinic acid 4-tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: EDC*HCl; HOBt / dimethylformamide

2: H₂; Pd/C / methanol; dimethylformamide

With palladium on activated charcoal; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(01)00841-1