Technology Process of (1S,2S,7R,8R)-10-Phenyl-4,9,11-trioxa-10-bora-tricyclo[6.3.1.02,7]dodecan-3-one
There total 8 articles about (1S,2S,7R,8R)-10-Phenyl-4,9,11-trioxa-10-bora-tricyclo[6.3.1.02,7]dodecan-3-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Molekularsieb 4A;
In
dichloromethane;
for 24h;
Heating;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 95 percent / H2 / 10percent Pd/C / ethyl acetate / Ambient temperature
2: 91 percent / LiAlH4 / tetrahydrofuran / 4 h / Heating
3: 63 percent / NaIO4 / H2O / 12 h / 50 °C
4: 29 percent / BaCO3, Br2 / H2O / 3 h
5: 74 percent / Molekularsieb 4A / CH2Cl2 / 24 h / Heating
With
sodium periodate; lithium aluminium tetrahydride; Molekularsieb 4A; hydrogen; bromine; barium carbonate;
palladium on activated charcoal;
In
tetrahydrofuran; dichloromethane; water; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 80 percent / Et3N / tetrahydrofuran / 5 h / Ambient temperature
2: 16 percent / LiAlH4 / tetrahydrofuran / 1 h / 0 °C
3: 84 percent / Hg(OCOCH3)2 / H2O; acetonitrile / 0.17 h
4: 29 percent / BaCO3, Br2 / H2O / 3 h
5: 74 percent / Molekularsieb 4A / CH2Cl2 / 24 h / Heating
With
lithium aluminium tetrahydride; Molekularsieb 4A; mercury(II) diacetate; bromine; triethylamine; barium carbonate;
In
tetrahydrofuran; dichloromethane; water; acetonitrile;
