(S)-4-fluoro-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-pyridin-4-yl-biphenyl-4-yl)-ethylamino]-pentanoic acid ((S)-1-cyano-2-phenyl-ethyl)-amide

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Chemical Name:(S)-4-fluoro-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-pyridin-4-yl-biphenyl-4-yl)-ethylamino]-pentanoic acid ((S)-1-cyano-2-phenyl-ethyl)-amide
CAS No.:1159488-87-5
Molecular Formula:C₃₄H₃₂F₄N₄O
Molecular Weight:588.648
Hs Code.:

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Chemical Property of (S)-4-fluoro-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-pyridin-4-yl-biphenyl-4-yl)-ethylamino]-pentanoic acid ((S)-1-cyano-2-phenyl-ethyl)-amide

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Technology Process of (S)-4-fluoro-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-pyridin-4-yl-biphenyl-4-yl)-ethylamino]-pentanoic acid ((S)-1-cyano-2-phenyl-ethyl)-amide

There total 2 articles about (S)-4-fluoro-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-pyridin-4-yl-biphenyl-4-yl)-ethylamino]-pentanoic acid ((S)-1-cyano-2-phenyl-ethyl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1045332-30-6
(4-(pyridine-4-yl)phenyl)boronic acid

: C₂₃H₂₄BrF₄N₃O

: 1159488-87-5
(S)-4-fluoro-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-pyridin-4-yl-biphenyl-4-yl)-ethylamino]-pentanoic acid ((S)-1-cyano-2-phenyl-ethyl)-amide

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate; In N,N-dimethyl-formamide; at 90 ℃;
DOI:10.1016/j.bmcl.2010.10.015