2-(4-METHYL-CYCLOHEXYL)-ETHYLAMINE

Base Information

• Chemical Name: 2-(4-METHYL-CYCLOHEXYL)-ETHYLAMINE
• CAS No.: 408312-01-6
• Molecular Formula: C₉H₁₉N
• Molecular Weight: 141.257
• Mol file: 408312-01-6.mol

Synonyms:

Chemical Property of 2-(4-METHYL-CYCLOHEXYL)-ETHYLAMINE

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

2-(4-METHYL-CYCLOHEXYL)ETHYLAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-METHYL-CYCLOHEXYL)-ETHYLAMINE

There total 5 articles about 2-(4-METHYL-CYCLOHEXYL)-ETHYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(p-tolyl)ethylamine (3261-62-9) → 2-(4-methyl-cyclohexyl)-ethylamine (76833-31-3,408312-01-6)

Guidance literature:

With acetic acid; platinum; Hydrogenation;

DOI:10.1021/ja01526a063

Reference yield:

(4-methylphenyl)acetonitrile (2947-61-7) → 2-(4-methyl-cyclohexyl)-ethylamine (76833-31-3,408312-01-6)

Guidance literature:

Multi-step reaction with 2 steps

1: platinum; acetic acid anhydride / Hydrogenation_.beim Erhitzen mit wss. HCl

2: platinum; acetic acid / Hydrogenation

With acetic anhydride; acetic acid; platinum;

DOI:10.1021/ja01526a063

Reference yield:

(cis-4-methyl-cyclohexyl)-acetic acid (7132-95-8) → 2-(cis-4-Methylcyclohexyl)ethylamine (76833-31-3,408312-01-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 82 percent / LiAlH₄ / diethyl ether

2: Pyridine

3: 1.) NaN₃, 2.) LiAlH₄ / 1.) DMSO, H₂O, 70 deg C, overnight, 2.) ether

With pyridine; lithium aluminium tetrahydride; sodium azide; In diethyl ether;

DOI:10.1021/jo00322a056

upstream raw materials:

2-(p-tolyl)ethylamine

(4-methylphenyl)acetonitrile

Toluene-4-sulfonic acid 2-(4-methyl-cyclohexyl)-ethyl ester

(cis-4-methyl-cyclohexyl)-acetic acid

Downstream raw materials:

trimethyl-[2-(4-methyl-cyclohexyl)-ethyl]-ammonium; iodide

Refernces