N⁴--β-D-arabinosylcytosine

Base Information

Chemical Name:N⁴--β-D-arabinosylcytosine
CAS No.:129835-34-3
Molecular Formula:C₁₇H₂₈N₅O₆P
Molecular Weight:429.413
Hs Code.:

N<sup>4</sup>-<bis(2,2-dimethyl-1-aziridinyl)phosphinyl>-β-D-arabinosylcytosine

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Suppliers and Price of N⁴--β-D-arabinosylcytosine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N⁴--β-D-arabinosylcytosine

Chemical Property:

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Technology Process of N⁴--β-D-arabinosylcytosine

There total 4 articles about N⁴--β-D-arabinosylcytosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 129835-33-2
N⁴--1-(2',3',5'-triacetyl-β-D-arabinosyl)cytosine

: 129835-34-3
N⁴--β-D-arabinosylcytosine

Guidance literature:: With propylamine; In methanol; at 0 - 25 ℃; for 5h;
DOI:10.1021/jm00171a039

Reference yield:

: 58227-71-7
1-(2,3,5-tri-O-acetyl-β-D-arabinofuranosyl)cytosine hydrochloride

: 129835-34-3
N⁴--β-D-arabinosylcytosine

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) Et₃N, 2.) POCl₃, Et₃N / 1.) THF, 25 min, 2.) 0-5 deg C, 45 min

2: Et₃N / tetrahydrofuran / 3 h / 0 - 25 °C

3: 78 percent / N-propylamine / methanol / 5 h / 0 - 25 °C

With propylamine; triethylamine; trichlorophosphate; In tetrahydrofuran; methanol;
DOI:10.1021/jm00171a039

Reference yield:

: C₁₅H₁₈Cl₂N₃O₉P

: 129835-34-3
N⁴--β-D-arabinosylcytosine

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / tetrahydrofuran / 3 h / 0 - 25 °C

2: 78 percent / N-propylamine / methanol / 5 h / 0 - 25 °C

With propylamine; triethylamine; In tetrahydrofuran; methanol;
DOI:10.1021/jm00171a039