N-(3-carboxypropanoyl)-β-phenyl-α-alanine acid chloride

Base Information

• Chemical Name: N-(3-carboxypropanoyl)-β-phenyl-α-alanine acid chloride
• CAS No.: 104818-51-1
• Molecular Formula: C₁₃H₁₄ClNO₄
• Molecular Weight: 283.711
• Mol file: 104818-51-1.mol

Synonyms:

Chemical Property of N-(3-carboxypropanoyl)-β-phenyl-α-alanine acid chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(3-carboxypropanoyl)-β-phenyl-α-alanine acid chloride

There total 2 articles about N-(3-carboxypropanoyl)-β-phenyl-α-alanine acid chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.4%

N-(3-carboxypropanoyl)-β-phenyl-α-alanine (5754-07-4,37590-83-3) → N-(3-carboxypropanoyl)-β-phenyl-α-alanine acid chloride (104818-51-1)

Guidance literature:

With thionyl chloride; for 5h; Heating;

DOI:10.1007/BF00579074

Reference yield:

Phenylalanine (150-30-1,25191-15-5,658-69-5,67675-33-6) → N-(3-carboxypropanoyl)-β-phenyl-α-alanine acid chloride (104818-51-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 83.5 percent / dioxane / Heating

2: 47.4 percent / SOCl₂ / 5 h / Heating

With thionyl chloride; In 1,4-dioxane;

DOI:10.1007/BF00579074

Reference yield: 32.4%

N-(3-carboxypropanoyl)-β-phenyl-α-alanine acid chloride (104818-51-1) → dihydrotestosterone ester of N-(3-carboxypropanoyl)-β-phenyl-α-alanine (104818-47-5)

Guidance literature:

With pyridine; at -5 ℃; for 2h;

DOI:10.1007/BF00579074

upstream raw materials:

N-(3-carboxypropanoyl)-β-phenyl-α-alanine

Phenylalanine

Downstream raw materials:

dihydrotestosterone ester of N-(3-carboxypropanoyl)-β-phenyl-α-alanine