3-benzyloxy-4-hydroxyxanthone

Base Information

• Chemical Name: 3-benzyloxy-4-hydroxyxanthone
• CAS No.: 110597-41-6
• Molecular Formula: C₂₀H₁₄O₄
• Molecular Weight: 318.329
• Mol file: 110597-41-6.mol

Synonyms:

Chemical Property of 3-benzyloxy-4-hydroxyxanthone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-benzyloxy-4-hydroxyxanthone

There total 1 articles about 3-benzyloxy-4-hydroxyxanthone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,4-dihydroxy-9H-xanthen-9-one (39731-48-1) + benzyl chloride (100-44-7) → 3-benzyloxy-4-hydroxyxanthone (110597-41-6)

Guidance literature:

With sodium hydrogencarbonate; sodium iodide; In acetone; for 24h; Heating;

Reference yield:

3-benzyloxy-4-hydroxyxanthone (110597-41-6) → (+/-)-(2R,3R)-2,3-dihydro-2-(hydroxymethyl)-3-(4-hydroxy-3-methoxyphenyl)-7H-[1,4]dioxino[5,6-c]xanthen-7-one (110597-45-0)

Guidance literature:

Multi-step reaction with 4 steps

1: 550 mg / K₂CO₃ / acetone / 6 h / Heating

2: 75 mg / H₂ / 10percent Pd/C / ethanol / 48 h / Ambient temperature

3: 40 mg / POCl₃ / 0.5 h / 40 °C

4: 6 mg / LAH / tetrahydrofuran / 2 h

With lithium aluminium tetrahydride; hydrogen; potassium carbonate; trichlorophosphate; palladium on activated charcoal; In tetrahydrofuran; ethanol; acetone;

Reference yield:

3-benzyloxy-4-hydroxyxanthone (110597-41-6) → ethyl 2-<9H-(3-hydroxy-9-oxo)xanthen-4-yl>oxy-3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propionate (110597-43-8,110618-96-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 550 mg / K₂CO₃ / acetone / 6 h / Heating

2: 75 mg / H₂ / 10percent Pd/C / ethanol / 48 h / Ambient temperature

With hydrogen; potassium carbonate; palladium on activated charcoal; In ethanol; acetone;

upstream raw materials:

3,4-dihydroxy-9H-xanthen-9-one

benzyl chloride

Downstream raw materials:

ethyl 2-<9H-(3-benzyloxy-9-oxo)xanthen-4-yl>oxy-3-oxo-3-(4-benzyloxy-3-methoxyphenyl)propionate

(+/-)-(2R,3R)-2,3-dihydro-2-(hydroxymethyl)-3-(4-hydroxy-3-methoxyphenyl)-7H-[1,4]dioxino[5,6-c]xanthen-7-one

ethyl 2-<9H-(3-hydroxy-9-oxo)xanthen-4-yl>oxy-3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propionate

2,3-dihydro-2-ethoxycarbonyl-3-(4-hydroxy-3-methoxyphenyl)-7H-1,4-dioxino-<2,3-c>xanthen-7-one

Refernces