4-Oxazolemethanol, 4,5-dihydro-2-phenyl-, benzoate (ester), (R)-

Base Information

Chemical Name:4-Oxazolemethanol, 4,5-dihydro-2-phenyl-, benzoate (ester), (R)-
CAS No.:148278-98-2
Molecular Formula:C₁₇H₁₅NO₃
Molecular Weight:281.311
Hs Code.:
DSSTox Substance ID:DTXSID301170540

Synonyms:DTXSID301170540;4-Oxazolemethanol, 4,5-dihydro-2-phenyl-, benzoate (ester), (R)-;148278-98-2

Suppliers and Price of 4-Oxazolemethanol, 4,5-dihydro-2-phenyl-, benzoate (ester), (R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Oxazolemethanol, 4,5-dihydro-2-phenyl-, benzoate (ester), (R)-

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:281.10519334
Heavy Atom Count:21
Complexity:382

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(N=C(O1)C2=CC=CC=C2)COC(=O)C3=CC=CC=C3
Isomeric SMILES:C1[C@@H](N=C(O1)C2=CC=CC=C2)COC(=O)C3=CC=CC=C3

Technology Process of 4-Oxazolemethanol, 4,5-dihydro-2-phenyl-, benzoate (ester), (R)-

There total 4 articles about 4-Oxazolemethanol, 4,5-dihydro-2-phenyl-, benzoate (ester), (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: (R)-2-amino-3-benzoyloxy-propan-1-ol hydrochloride

: 825-60-5
benzimidic acid ethyl ester

: 148278-98-2
(R)-4-(benzoyloxymethyl)-2-phenyl-oxazoline

Guidance literature:: In 1,2-dichloro-ethane; for 18h; Heating;
DOI:10.1055/s-1993-25842

Reference yield:

: 82936-49-0
(R)-2-phenyl-4-hydroxymethyl-4,5-dihydrooxazole

: 148278-98-2
(R)-4-(benzoyloxymethyl)-2-phenyl-oxazoline

Guidance literature:: Multi-step reaction with 2 steps

1: 99.3 percent / HCl / tetrahydrofuran / 24 h / Ambient temperature

2: 84 percent / 1,2-dichloro-ethane / 18 h / Heating

With hydrogenchloride; In tetrahydrofuran; 1,2-dichloro-ethane;
DOI:10.1055/s-1993-25842

Reference yield:

: 825-60-5
benzimidic acid ethyl ester

: 148278-98-2
(R)-4-(benzoyloxymethyl)-2-phenyl-oxazoline

Guidance literature:: Multi-step reaction with 4 steps

1: 93 percent / 1,2-dichloro-ethane / 20 h / Heating

2: 91 percent / diisobutylaluminium hydride / tetrahydrofuran / 2 h / 0 °C

3: 99.3 percent / HCl / tetrahydrofuran / 24 h / Ambient temperature

4: 84 percent / 1,2-dichloro-ethane / 18 h / Heating

With hydrogenchloride; diisobutylaluminium hydride; In tetrahydrofuran; 1,2-dichloro-ethane;
DOI:10.1055/s-1993-25842