(1(1')E)-1-deoxy-1-(dibenzyloxyphosphoryl)fluoromethylidene-2,3,5,6-tetra-O-tert-butyldimethylsilyl-D-galactofuranose

Base Information

• Chemical Name: (1(1')E)-1-deoxy-1-(dibenzyloxyphosphoryl)fluoromethylidene-2,3,5,6-tetra-O-tert-butyldimethylsilyl-D-galactofuranose
• CAS No.: 890028-52-1
• Molecular Formula: C₄₅H₈₀FO₈PSi₄
• Molecular Weight: 911.44
• Mol file: 890028-52-1.mol

Synonyms:

Chemical Property of (1(1')E)-1-deoxy-1-(dibenzyloxyphosphoryl)fluoromethylidene-2,3,5,6-tetra-O-tert-butyldimethylsilyl-D-galactofuranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1(1')E)-1-deoxy-1-(dibenzyloxyphosphoryl)fluoromethylidene-2,3,5,6-tetra-O-tert-butyldimethylsilyl-D-galactofuranose

There total 2 articles about (1(1')E)-1-deoxy-1-(dibenzyloxyphosphoryl)fluoromethylidene-2,3,5,6-tetra-O-tert-butyldimethylsilyl-D-galactofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(1(1')Z)-1-(dibenzyloxyphosphoryl)methylidene-2,3,4,6-tetra-O-tert-butyldimethylsilyl-D-galactofuranose (724422-85-9) → 1-(dibenzyloxyphosphoryl)fluoromethyl-2,3,5,6-tetra-O-tert-butyldimethylsilyl-D-galactofuranose + (1(1')E)-1-deoxy-1-(dibenzyloxyphosphoryl)fluoromethylidene-2,3,5,6-tetra-O-tert-butyldimethylsilyl-D-galactofuranose (890028-52-1) + (1(1')Z)-1-deoxy-1-(dibenzyloxyphosphoryl)fluoromethylidene-2,3,5,6-tetra-O-tert-butyldimethylsilyl-D-galactofuranose (890028-51-0)

Guidance literature:

With 4 A molecular sieve; In nitromethane; acetonitrile; at 30 ℃; for 12h; Further Variations:; Reagents; Solvents; Temperatures; time; Product distribution;

DOI:10.1002/chem.200500991

Reference yield: 46.0%

1-(dibenzyloxyphosphoryl)fluoromethyl-2,3,5,6-tetra-O-tert-butyldimethylsilyl-D-galactofuranose → (1(1')E)-1-deoxy-1-(dibenzyloxyphosphoryl)fluoromethylidene-2,3,5,6-tetra-O-tert-butyldimethylsilyl-D-galactofuranose (890028-52-1) + (1(1')Z)-1-deoxy-1-(dibenzyloxyphosphoryl)fluoromethylidene-2,3,5,6-tetra-O-tert-butyldimethylsilyl-D-galactofuranose (890028-51-0)

Guidance literature:

With pyridine; dmap; trifluoroacetic anhydride; In dichloromethane; at 35 ℃; for 24h; Further Variations:; Reagents; Solvents; Temperatures; time; Product distribution;

DOI:10.1002/chem.200500991

upstream raw materials:

(1(1')Z)-1-(dibenzyloxyphosphoryl)methylidene-2,3,4,6-tetra-O-tert-butyldimethylsilyl-D-galactofuranose