2,4,4'-trimethoxy-6-hydroxy-5-(tricarbonyl[(1'',2'',3'',4''-η)-2''-methoxy-1'',3''-cyclohexa-5''α-dienyl]iron(0))chalcone

Base Information

• Chemical Name: 2,4,4'-trimethoxy-6-hydroxy-5-(tricarbonyl[(1'',2'',3'',4''-η)-2''-methoxy-1'',3''-cyclohexa-5''α-dienyl]iron(0))chalcone
• CAS No.: 557762-90-0
• Molecular Formula: C₂₈H₂₆FeO₉
• Molecular Weight: 562.356
• Mol file: 557762-90-0.mol

Synonyms:

Chemical Property of 2,4,4'-trimethoxy-6-hydroxy-5-(tricarbonyl[(1'',2'',3'',4''-η)-2''-methoxy-1'',3''-cyclohexa-5''α-dienyl]iron(0))chalcone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,4,4'-trimethoxy-6-hydroxy-5-(tricarbonyl[(1'',2'',3'',4''-η)-2''-methoxy-1'',3''-cyclohexa-5''α-dienyl]iron(0))chalcone

There total 1 articles about 2,4,4'-trimethoxy-6-hydroxy-5-(tricarbonyl[(1'',2'',3'',4''-η)-2''-methoxy-1'',3''-cyclohexa-5''α-dienyl]iron(0))chalcone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

tricarbonyl(η(5)-2-methoxycyclohexadienyl)iron hexafluorophosphate (51508-59-9) + 4',5,7-trimethoxyflavanone (66074-95-1,38302-15-7) → 2,4,4'-trimethoxy-6-hydroxy-5-(tricarbonyl[(1'',2'',3'',4''-η)-2''-methoxy-1'',3''-cyclohexa-5''α-dienyl]iron(0))chalcone (557762-90-0)

Guidance literature:

With copper(I) bromide dimethylsulfide complex; ammonium chloride; lithium hexamethyldisilazane; In tetrahydrofuran; byproducts: 2,4,4'-trimethoxy-6-hydroxychalcone; (N2); addn. of THF soln. of 4',5,7-trimethoxyflavanone to soln. of LiN(i-Pr)2 at -78°C, stirring for 15 min, addn. of CuBr*Me2S; stirringfor 1 h at -78°C; addn. of (Fe(C6H6OMe)(CO)3)PF6; warming to roo m temp. for 1 h, addn. of aq. NH4Cl; extn. with ether, drying of combining extracts over MgSO4, concn. under reduced pressure, chromy. on silica gel; elution with mixt CH2Cl2; as oil; elem. anal.;

DOI:10.1016/S0022-328X(02)02146-0

upstream raw materials:

tricarbonyl(η(5)-2-methoxycyclohexadienyl)iron hexafluorophosphate

4',5,7-trimethoxyflavanone