Ethyl 4-(4-chloroanilino)-4-oxobutanoate

Base Information

Chemical Name:Ethyl 4-(4-chloroanilino)-4-oxobutanoate
CAS No.:17722-53-1
Molecular Formula:C₁₂H₁₄ClNO₃
Molecular Weight:255.701
Hs Code.:
DSSTox Substance ID:DTXSID701246872
Mol file:17722-53-1.mol

Synonyms:ethyl 4-(4-chloroanilino)-4-oxobutanoate;ethyl 4-[(4-chlorophenyl)amino]-4-oxobutanoate;DTXSID701246872;STK043149;AKOS000488349;17722-53-1;ethyl 3-[(4-chlorophenyl)carbamoyl]propanoate;AN-329/13779692;SR-01000465870;SR-01000465870-1

Suppliers and Price of Ethyl 4-(4-chloroanilino)-4-oxobutanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Aronis compounds
ethyl4-[(4-chlorophenyl)amino]-4-oxobutanoate
50mg
$ 50.00

Total 3 raw suppliers

Chemical Property of Ethyl 4-(4-chloroanilino)-4-oxobutanoate

Chemical Property:

Melting Point:114 °C
Boiling Point:431.2±30.0 °C(Predicted)
PKA:13.59±0.70(Predicted)
Density:1.253±0.06 g/cm3(Predicted)
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:255.0662210
Heavy Atom Count:17
Complexity:263

Purity/Quality:

99% ^*data from raw suppliers

ethyl4-[(4-chlorophenyl)amino]-4-oxobutanoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)CCC(=O)NC1=CC=C(C=C1)Cl

Technology Process of Ethyl 4-(4-chloroanilino)-4-oxobutanoate

There total 7 articles about Ethyl 4-(4-chloroanilino)-4-oxobutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 544476-12-2
C₁₂H₁₂ClNO₃

: 17722-53-1
3-(4-Chlor-phenylcarbamoyl)-propionsaeure-aethylester

Guidance literature:: With magnesium; In methanol; at 20 ℃;

Reference yield:

: 106-47-8
4-chloro-aniline

: 17722-53-1
3-(4-Chlor-phenylcarbamoyl)-propionsaeure-aethylester

Guidance literature:: Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / neat (no solvent, solid phase) / 0.13 h / Milling; Green chemistry

2: potassium carbonate / neat (no solvent, solid phase) / 0.13 h / Milling; Green chemistry

With potassium carbonate; toluene-4-sulfonic acid; In neat (no solvent, solid phase);

Reference yield:

: 7242-16-2
N-4-chlorophenyl-maleamic acid

: 17722-53-1
3-(4-Chlor-phenylcarbamoyl)-propionsaeure-aethylester

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / 0.25 h / 0 - 5 °C

2: magnesium / methanol / 20 °C

With thionyl chloride; magnesium; In methanol;