4-Nitro-3-hydroxy-phenacylbromid

Base Information

• Chemical Name: 4-Nitro-3-hydroxy-phenacylbromid
• CAS No.: 5086-77-1
• Molecular Formula: C₈H₆BrNO₄
• Molecular Weight: 260.044
• Mol file: 5086-77-1.mol

Synonyms:

Chemical Property of 4-Nitro-3-hydroxy-phenacylbromid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Nitro-3-hydroxy-phenacylbromid

There total 2 articles about 4-Nitro-3-hydroxy-phenacylbromid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(5-hydroxy-4-nitrophenyl)ethanone (89942-63-2) → 4-Nitro-3-hydroxy-phenacylbromid (5086-77-1)

Guidance literature:

With copper(ll) bromide; In ethyl acetate; Reflux; Inert atmosphere;

DOI:10.1021/jm301793a

Reference yield:

→ 4-Nitro-3-hydroxy-phenacylbromid (5086-77-1)

Guidance literature:

/BRN= 504379/, Br2;

Reference yield:

4-Nitro-3-hydroxy-phenacylbromid (5086-77-1) → C9H8N2O2S (1435386-92-7)

Guidance literature:

Multi-step reaction with 3 steps

1: acetone / 0.5 h / 20 °C / Inert atmosphere

2: sulfuric acid; acetic acid / 1 h / 100 °C / Inert atmosphere

3: iron; ammonium chloride / ethanol / 1 h / 80 °C / Inert atmosphere

With sulfuric acid; iron; ammonium chloride; acetic acid; In ethanol; acetone;

DOI:10.1021/jm301793a

upstream raw materials:

1-(5-hydroxy-4-nitrophenyl)ethanone

Downstream raw materials:

C₉H₈N₂O₂S

C₁₃H₁₀N₂O₄S₃

Refernces