4-(1H-1,2,3-benzotriazol-1-yl)-5-hydroxyphthalonitrile

Base Information

• Chemical Name: 4-(1H-1,2,3-benzotriazol-1-yl)-5-hydroxyphthalonitrile
• CAS No.: 492447-33-3
• Molecular Formula: C₁₄H₇N₅O
• Molecular Weight: 261.242
• Mol file: 492447-33-3.mol

Synonyms:

Chemical Property of 4-(1H-1,2,3-benzotriazol-1-yl)-5-hydroxyphthalonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(1H-1,2,3-benzotriazol-1-yl)-5-hydroxyphthalonitrile

There total 4 articles about 4-(1H-1,2,3-benzotriazol-1-yl)-5-hydroxyphthalonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-(1H-1,2,3-benzotriazol-1-yl)-5-nitrophthalonitrile (274924-71-9) → 4-(1-benzotriazolyl)-5-hydroxyphthalonitrile (492447-33-3)

Guidance literature:

With potassium carbonate; sodium nitrite; In water; N,N-dimethyl-formamide; at 70 ℃; for 0.5h;

DOI:10.1070/MC2002v012n02ABEH001538

Reference yield:

1,2-diamino-benzene (95-54-5) → 4-(1-benzotriazolyl)-5-hydroxyphthalonitrile (492447-33-3)

Guidance literature:

Multi-step reaction with 3 steps

1: Et₃N / propan-2-ol / Heating

2: NaNO₂ / acetic acid; H₂O / 3 h / 70 °C

3: 90 percent / NaNO₂; K₂CO₃ / H₂O; dimethylformamide / 0.5 h / 70 °C

With potassium carbonate; triethylamine; sodium nitrite; In water; acetic acid; N,N-dimethyl-formamide; isopropyl alcohol;

DOI:10.1070/MC2002v012n02ABEH001538

Reference yield:

4-bromo-5-nitrophthalonitrile (206268-72-6) → 4-(1-benzotriazolyl)-5-hydroxyphthalonitrile (492447-33-3)

Guidance literature:

Multi-step reaction with 3 steps

1: Et₃N / propan-2-ol / Heating

2: NaNO₂ / acetic acid; H₂O / 3 h / 70 °C

3: 90 percent / NaNO₂; K₂CO₃ / H₂O; dimethylformamide / 0.5 h / 70 °C

With potassium carbonate; triethylamine; sodium nitrite; In water; acetic acid; N,N-dimethyl-formamide; isopropyl alcohol;

DOI:10.1070/MC2002v012n02ABEH001538

upstream raw materials:

4-(1H-1,2,3-benzotriazol-1-yl)-5-nitrophthalonitrile

1,2-diamino-benzene

4-bromo-5-nitrophthalonitrile

4-[(2-aminophenyl)amino]-5-nitro-phthalodinitrile