3-Oxo-5β-carda-8(14),20(22)-dienolide

Base Information

• Chemical Name: 3-Oxo-5β-carda-8(14),20(22)-dienolide
• CAS No.: 4521-89-5
• Molecular Formula: C₂₃H₃₀O₃
• Molecular Weight: 354.489
• Mol file: 4521-89-5.mol

Synonyms:5b-Carda-8(14),20(22)-dienolide,3-oxo- (8CI); 3-Digitoxigenone, 8(14)-anhydro-

Chemical Property of 3-Oxo-5β-carda-8(14),20(22)-dienolide

Chemical Property:

• PSA: 43.37000
• LogP: 4.76180

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Oxo-5β-carda-8(14),20(22)-dienolide

There total 3 articles about 3-Oxo-5β-carda-8(14),20(22)-dienolide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 21-hydroxy-3-oxo-24-nor-5β-chola-8(14),20(22)c-dien-23-oic acid-lactone (4521-89-5)

Guidance literature:

With chromium(VI) oxide; sulfuric acid;

DOI:10.1246/bcsj.12.436

Reference yield:

Δ14-anhydrodigitoxigenin (4427-79-6) → 21-hydroxy-3-oxo-24-nor-5β-chola-8(14),20(22)c-dien-23-oic acid-lactone (4521-89-5)

Guidance literature:

With chromium(VI) oxide; sulfuric acid; acetic acid;

DOI:10.1039/jr9350001050

Reference yield:

(+)-digitoxigenin (143-62-4) → 21-hydroxy-3-oxo-24-nor-5β-chola-8(14),20(22)c-dien-23-oic acid-lactone (4521-89-5)

Guidance literature:

Multi-step reaction with 2 steps

1: aq.-ethanolic sulfuric acid

2: acetic acid; chromium (VI)-oxide; aqueous sulfuric acid

With chromium(VI) oxide; sulfuric acid; acetic acid;

DOI:10.1039/jr9350001050

upstream raw materials:

Δ¹⁴-anhydrodigitoxigenin

(+)-digitoxigenin