Technology Process of 5-(benzyloxy)-7,7-dimethyl-1,3,8-nonatriene
There total 4 articles about 5-(benzyloxy)-7,7-dimethyl-1,3,8-nonatriene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1) lithium diisopropylamide / 1) THF, -78 deg C, 1 h, 2) 20 min, -78 deg C
2: 85 percent / methanesulfonyl chloride, NEt3 / CH2Cl2 / 1) 0 deg C, 1.5 h, 2) 2 h, room temperature
3: 98 percent / LiAlH4 / diethyl ether
4: 1) 50percent NaH, 2) tetrabutylammonium iodide / 1) THF, 10 min, room temperature, 2) room temperature, 5 h
With
lithium aluminium tetrahydride; tetra-(n-butyl)ammonium iodide; sodium hydride; methanesulfonyl chloride; triethylamine; lithium diisopropyl amide;
In
diethyl ether; dichloromethane;
DOI:10.1021/jo00008a045
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 98 percent / LiAlH4 / diethyl ether
2: 1) 50percent NaH, 2) tetrabutylammonium iodide / 1) THF, 10 min, room temperature, 2) room temperature, 5 h
With
lithium aluminium tetrahydride; tetra-(n-butyl)ammonium iodide; sodium hydride;
In
diethyl ether;
DOI:10.1021/jo00008a045
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 85 percent / methanesulfonyl chloride, NEt3 / CH2Cl2 / 1) 0 deg C, 1.5 h, 2) 2 h, room temperature
2: 98 percent / LiAlH4 / diethyl ether
3: 1) 50percent NaH, 2) tetrabutylammonium iodide / 1) THF, 10 min, room temperature, 2) room temperature, 5 h
With
lithium aluminium tetrahydride; tetra-(n-butyl)ammonium iodide; sodium hydride; methanesulfonyl chloride; triethylamine;
In
diethyl ether; dichloromethane;
DOI:10.1021/jo00008a045
