Technology Process of C23H23F3N4O3
There total 4 articles about C23H23F3N4O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: ammonium formate; 10% Pd/C / methanol / Heating
2: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine / N,N-dimethyl-formamide
With
10% Pd/C; ammonium formate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine;
In
methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.08.031
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 / isopropyl alcohol / Heating
2: ammonium formate; 10% Pd/C / methanol / Heating
3: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine / N,N-dimethyl-formamide
With
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; 10% Pd/C; ammonium formate; potassium carbonate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine;
In
methanol; N,N-dimethyl-formamide; isopropyl alcohol;
1: |Suzuki Coupling;
DOI:10.1016/j.bmcl.2012.08.031
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium carbonate; potassium iodide / acetonitrile
2: potassium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 / isopropyl alcohol / Heating
3: ammonium formate; 10% Pd/C / methanol / Heating
4: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine / N,N-dimethyl-formamide
With
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; 10% Pd/C; ammonium formate; potassium carbonate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; potassium iodide;
In
methanol; N,N-dimethyl-formamide; isopropyl alcohol; acetonitrile;
2: |Suzuki Coupling;
DOI:10.1016/j.bmcl.2012.08.031