Technology Process of 6,7-di-O-benzyl-8,9-O-isopropylidene-1,3,4,5-tetradeoxy-D-ribo-non-4-eno-2-ulose ethylene acetal
There total 6 articles about 6,7-di-O-benzyl-8,9-O-isopropylidene-1,3,4,5-tetradeoxy-D-ribo-non-4-eno-2-ulose ethylene acetal which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 55 percent / propan-1-ol / Heating
2: 1.) n-butyllithium / 1.) hexane, from -20 deg C to -10 deg C; 2.) THF, 5 deg C, 12 h
With
n-butyllithium;
In
propan-1-ol;
DOI:10.1016/S0040-4020(01)86784-3
- Guidance literature:
-
Multi-step reaction with 5 steps
2: 89 percent / p-toluenesulfonic acid*H2O / dimethylformamide / 1 h / 0 °C
3: 95 percent / NaH, methyltriphenylphosphonium iodide / tetrahydrofuran / 12 h / Ambient temperature
4: 91 percent / s-collidine, methyl iodide / H2O; acetone / 4 h / 40 °C
5: 1.) n-butyllithium / 1.) hexane, from -20 deg C to -10 deg C; 2.) THF, 5 deg C, 12 h
With
2,4,6-trimethyl-pyridine; n-butyllithium; methyl-triphenylphosphonium iodide; sodium hydride; toluene-4-sulfonic acid; methyl iodide;
In
tetrahydrofuran; water; N,N-dimethyl-formamide; acetone;
DOI:10.1016/S0040-4020(01)86784-3
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 89 percent / p-toluenesulfonic acid*H2O / dimethylformamide / 1 h / 0 °C
2: 95 percent / NaH, methyltriphenylphosphonium iodide / tetrahydrofuran / 12 h / Ambient temperature
3: 91 percent / s-collidine, methyl iodide / H2O; acetone / 4 h / 40 °C
4: 1.) n-butyllithium / 1.) hexane, from -20 deg C to -10 deg C; 2.) THF, 5 deg C, 12 h
With
2,4,6-trimethyl-pyridine; n-butyllithium; methyl-triphenylphosphonium iodide; sodium hydride; toluene-4-sulfonic acid; methyl iodide;
In
tetrahydrofuran; water; N,N-dimethyl-formamide; acetone;
DOI:10.1016/S0040-4020(01)86784-3
